Literature DB >> 1588679

Buflomedil intoxication: the little-known risk.

R Martínez-Sierra1, B Lara, A Torres.   

Abstract

A life-threatening intoxication, requiring ventilatory support, is reported from the ingestion of 3.05 g of buflomedil, a peripheral vasodilator. Buflomedil at a dosage of 50 mg/kg weight produces seizures. Hypotension is not a specific symptom of intoxication. Buflomedil poisoning can be easily confused with other drugs, especially tricyclic antidepressants.

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Year:  1992        PMID: 1588679     DOI: 10.3109/15563659209038641

Source DB:  PubMed          Journal:  J Toxicol Clin Toxicol        ISSN: 0731-3810


  4 in total

1.  Bias in benefit-risk appraisal in older products: the case of buflomedil for intermittent claudication.

Authors:  Tine L M De Backer; Robert H Vander Stichele; Luc M Van Bortel
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

2.  Acute buflomedil intoxication: a critically life-threatening condition.

Authors:  P Y Gueugniaud; H Roux; P Petit
Journal:  Intensive Care Med       Date:  1995-05       Impact factor: 17.440

3.  Buflomedil poisoning: five cases with cardiotoxicity.

Authors:  A Legras; R Piquemal; Y Furet; P F Dequin; D Perrotin
Journal:  Intensive Care Med       Date:  1996-01       Impact factor: 17.440

Review 4.  Acute buflomedil intoxication: a life-threatening condition.

Authors:  A Alberti; S Valenti; F Gallo; M Petolillo; D Del Monte
Journal:  Intensive Care Med       Date:  1994       Impact factor: 17.440

  4 in total

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