| Literature DB >> 15886049 |
Janice L Walker1, Alaina K Fournier, Richard K Assoian.
Abstract
The proliferation of most non-transformed cell types requires cell adhesion and cellular tension as well as exposure to mitogenic growth factors. Integrins and cadherins provide the adhesion signals, which ultimately allow for the cytoskeletal changes that control cellular tension. This review discusses the roles of integrins, cadherins, and the actin cytoskeleton as mediators of the mechanical tension critical for growth factor-dependent signaling and cell cycle progression.Mesh：
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Year: 2005 PMID： 15886049 DOI： 10.1016/j.cytogfr.2005.03.003
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638