Literature DB >> 15884625

Fatty liver in obese children: prevalence and correlation with anthropometric measurements and hyperlipidemia.

Nur Arslan1, Benal Büyükgebiz, Yeşim Oztürk, Handan Cakmakçi.   

Abstract

The aim of this study was to evaluate the correlation of ultrasonography-proven fatty liver with liver functions, serum lipid levels and anthropometric measurements in children with exogenous obesity. Three hundred and twenty-two patients (183 girls, 56.8%) with a mean age of 11.4+/-3.2 years (4-18 years) who presented with the complaint of obesity were enrolled. In 38 (11.8%) patients, increased liver echogenicity resembling fatty liver was found (Group 1). The body mass index percentages of group 1 patients were significantly higher than of those without fatty liver (Group 2) (157.7+/-18.0 vs 151.3+/-17.8, p=0.038). Alanine and aspartate aminotransferase levels of group 1 patients were significantly higher than of group 2 (p=0.002 vs p=0.028, respectively). Triglyceride levels were significantly higher in group 1 patients (120.8+/-88.8 vs 100.5+/-58.5 mg/dl, p=0.044). In conclusion, ultrasonography is an easy and noninvasive method for the diagnosis of fatty liver in children with obesity. Body mass index and serum lipids were higher in group 1 patients. The diagnosis and early treatment of obesity in childhood is important for the prevention and better treatment of related complications. Thus, ultrasonography should be a part of the early evaluation of obese children.

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Year:  2005        PMID: 15884625

Source DB:  PubMed          Journal:  Turk J Pediatr        ISSN: 0041-4301            Impact factor:   0.552


  12 in total

1.  Hepatic artery resistance in children with obesity and fatty liver.

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Review 2.  Obesity, fatty liver disease and intestinal microbiota.

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3.  A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells.

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4.  Diagnosis and treatment of pediatric nonalcoholic steatohepatitis and the implications for bariatric surgery.

Authors:  Perrie E Pardee; Joel E Lavine; Jeffrey B Schwimmer
Journal:  Semin Pediatr Surg       Date:  2009-08       Impact factor: 2.754

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6.  Evaluation of serum xenin and ghrelin levels and their relationship with nonalcoholic fatty liver disease and insulin resistance in obese adolescents.

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7.  Current status of childhood obesity and its associated morbidities in Turkey.

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Journal:  J Clin Res Pediatr Endocrinol       Date:  2012-03

8.  Fatty liver in children.

Authors:  Mandana Rafeey; Fakhrossadat Mortazavi; Nafiseh Mogaddasi; Ghergherehchi Robabeh; Shamsi Ghaffari; Alka Hasani
Journal:  Ther Clin Risk Manag       Date:  2009-05-20       Impact factor: 2.423

9.  Prevalence of Dyslipidemia and Associated Factors in Obese Children and Adolescents.

Authors:  Selin Elmaoğulları; Derya Tepe; Seyit Ahmet Uçaktürk; Fatma Karaca Kara; Fatma Demirel
Journal:  J Clin Res Pediatr Endocrinol       Date:  2015-09

10.  Alanine aminotransferase elevation in obese infants and children: a marker of early onset non alcoholic Fatty liver disease.

Authors:  Guido Engelmann; Georg Friedrich Hoffmann; Juergen Grulich-Henn; Ulrike Teufel
Journal:  Hepat Mon       Date:  2014-04-07       Impact factor: 0.660

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