Literature DB >> 1588322

The P gene of the porcine paramyxovirus LPMV encodes three possible polypeptides P, V and C: the P protein mRNA is edited.

M Berg1, B Hjertner, J Moreno-López, T Linné.   

Abstract

The nucleotide sequence of the P gene of the porcine paramyxovirus La-Piedad-Michoacan-Mexico virus (LPMV) was analysed. Three long open reading frames (ORFs) were found in the mRNA sense. Insertion of two G residues is necessary to obtain an ORF encoding the P protein, which gives a P protein of 404 amino acids with a calculated Mr of 42475. This form of editing was demonstrated, two non-templated G residues being added in a portion of the mRNA transcripts. The LPMV V protein, which has a conserved cysteine-rich C-terminal region, is encoded by an exact copy of the P gene. The third ORF has the capacity to encode a protein of 126 amino acids, which may resemble the C proteins found in some paramyxoviruses. The ORF starts from an AUG codon down-stream of the first AUG codon of the P/V ORF.

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Year:  1992        PMID: 1588322     DOI: 10.1099/0022-1317-73-5-1195

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  11 in total

1.  Analysis of the fusion protein gene of the porcine rubulavirus LPMV: comparative analysis of paramyxovirus F proteins.

Authors:  M Berg; A C Bergvall; M Svenda; A Sundqvist; J Moreno-López; T Linné
Journal:  Virus Genes       Date:  1997       Impact factor: 2.332

2.  Rinderpest viruses lacking the C and V proteins show specific defects in growth and transcription of viral RNAs.

Authors:  M D Baron; T Barrett
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

3.  The porcine paramyxovirus LPM specifically recognizes sialyl (alpha 2,3) lactose-containing structures.

Authors:  J Reyes-Leyva; P Hernández-Jáuregui; L F Montaño; E Zenteno
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

4.  Molecular characterisation of Porcine rubulavirus (PorPV) isolates from different outbreaks in Mexico.

Authors:  S Cuevas-Romero; J F Rivera-Benítez; A-L Blomström; M Ramliden; E Hernández-Baumgarten; P Hernández-Jáuregui; H Ramírez-Mendoza; M Berg
Journal:  Virus Genes       Date:  2016-01-04       Impact factor: 2.332

5.  Establishment and characterisation of a porcine rubulavirus (LPMV) persistent infection in porcine kidney cells.

Authors:  B Hjertner; T Linné; J Moreno-López
Journal:  Acta Vet Scand       Date:  1997       Impact factor: 1.695

6.  La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation.

Authors:  Giuseppe Pisanelli; Maudry Laurent-Rolle; Balaji Manicassamy; Alan Belicha-Villanueva; Juliet Morrison; Bernardo Lozano-Dubernard; Felipa Castro-Peralta; Giuseppe Iovane; Adolfo García-Sastre
Journal:  Virus Res       Date:  2015-11-03       Impact factor: 3.303

7.  The mumps virus V protein is unstable in virus infected cells.

Authors:  A Hu; S Schwartz; G Utter; C Orvell; J Kövamees; E Norrby
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

Review 8.  Evolutionary history of cotranscriptional editing in the paramyxoviral phosphoprotein gene.

Authors:  Jordan Douglas; Alexei J Drummond; Richard L Kingston
Journal:  Virus Evol       Date:  2021-03-27

9.  Molecular and epidemiological studies of Porcine rubulavirus infection - an overview.

Authors:  Julieta Sandra Cuevas-Romero; Anne-Lie Blomström; Mikael Berg
Journal:  Infect Ecol Epidemiol       Date:  2015-11-18

10.  Development of a real-time RT-PCR method for detection of porcine rubulavirus (PoRV-LPMV).

Authors:  Sandra Cuevas-Romero; Anne-Lie Blomström; Arcelia Alvarado; Pablo Hernández-Jauregui; Francisco Rivera-Benitez; Humberto Ramírez-Mendoza; Mikael Berg
Journal:  J Virol Methods       Date:  2013-01-07       Impact factor: 2.014

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