Literature DB >> 15882851

Syntheses of chlorogenin 6alpha-O-acyl-3-O-beta-chacotriosides and their antitumor activities.

Yichun Zhang1, Yingxia Li, Tiantian Guo, Huashi Guan, Jiwei Shi, Qiang Yu, Biao Yu.   

Abstract

Chlorogenin 3-O-beta-chacotrioside (1) and its 6alpha-O-acyl derivatives (2-6) were concisely synthesized. Introduction of a hydroxyl or acyloxy group onto the C-6 of the steroidal aglycone of dioscin decreased significantly the cytotoxicity of the parent saponin (dioscin).

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Year:  2005        PMID: 15882851     DOI: 10.1016/j.carres.2005.03.019

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  1 in total

1.  Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins.

Authors:  Balla Sylla; Serge Lavoie; Jean Legault; Charles Gauthier; André Pichette
Journal:  RSC Adv       Date:  2019-12-02       Impact factor: 4.036

  1 in total

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