| Literature DB >> 15882253 |
S Ananth Karumanchi1, Sharon E Maynard, Isaac E Stillman, Franklin H Epstein, Vikas P Sukhatme.
Abstract
Preeclampsia is a syndrome that affects 5% of all pregnancies, producing substantial maternal and perinatal morbidity and mortality. The aim of this review is to summarize our current understanding of the pathogenesis of preeclampsia with special emphasis on the recent discovery that circulating anti-angiogenic proteins of placental origin may play an important role in the pathogenesis of proteinuria and hypertension of preeclampsia.Entities:
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Year: 2005 PMID: 15882253 DOI: 10.1111/j.1523-1755.2005.00316.x
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612