Literature DB >> 15881531

The apparent inversion time for optimal delayed enhancement magnetic resonance imaging differs between the right and left ventricles.

Milind Y Desai1, Sandeep Gupta, Chandra Bomma, Harikrishna Tandri, Thomas K Foo, Joao A C Lima, David A Bluemke.   

Abstract

BACKGROUND: Delayed post-contrast magnetic resonance (MR) imaging involves suppression of signal from myocardium using inversion times (TI) between 150-225 ms, when the myocardium appears dark and fibrotic scar appears bright. We noticed that at a TI optimized for signal suppression of the left ventricle (LV), the right ventricle (RV) appeared brighter.
PURPOSE: The purpose of this study was to evaluate the TI for signal suppression in RV compared to LV, and to try and identify the cause of this observation. Methods. We studied 31 patients (ages ranged from 17-79 years, 11 females) who had an MR scan on a 1.5 T GE scanner. Delayed post-contrast short-axis images were obtained 20 minutes after injection of 0.2 mmol/kg of intravenous gadolinium chelate. TI optimization was performed by acquiring a range of TI times within a single breath hold, in increments of 25 msec. The TI time that resulted in lowest signal for the RV arid LV was recorded.
RESULTS: With the imaging sequence employed, the TI leading to LV signal suppression ranged from 150-225 ms. At the TI that resulted in LV signal suppression, the corrected signal from the RV was significantly higher as compared to the LV (29 +/- 13 au vs. 15 +/- 8 au, p < 0.001). The findings were similar using only the body coil. The TI required to suppress the RV was usually < or =150 msec. The observation persisted before and after gadolinium infusion.
CONCLUSION: The TI for myocardial signal suppression appears to be different between LV and RV. Potential mechanisms include partial volume averaging with fat or blood pool (related to increased trabeculation) in the RV. Alternatively, increased blood pool signal (within Thebesian veins or arterioluminal communications) in RV compared to LV leads to altered TI times due to similar partial volume effects.

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Year:  2005        PMID: 15881531     DOI: 10.1081/jcmr-200053534

Source DB:  PubMed          Journal:  J Cardiovasc Magn Reson        ISSN: 1097-6647            Impact factor:   5.364


  10 in total

1.  Utility of cardiac magnetic resonance (CMR) in the evaluation of right ventricular (RV) involvement in patients with myocardial infarction (MI).

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2.  Association of regional epicardial right ventricular electrogram voltage amplitude and late gadolinium enhancement distribution on cardiac magnetic resonance in patients with arrhythmogenic right ventricular cardiomyopathy: Implications for ventricular tachycardia ablation.

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Review 3.  Magnetic resonance imaging in the evaluation of non-ischemic cardiomyopathies: current applications and future perspectives.

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9.  Guidelines and protocols for cardiovascular magnetic resonance in children and adults with congenital heart disease: SCMR expert consensus group on congenital heart disease.

Authors:  Sohrab Fratz; Taylor Chung; Gerald F Greil; Margaret M Samyn; Andrew M Taylor; Emanuela R Valsangiacomo Buechel; Shi-Joon Yoo; Andrew J Powell
Journal:  J Cardiovasc Magn Reson       Date:  2013-06-13       Impact factor: 5.364

10.  Late gadolinium enhancement of the right ventricular myocardium: is it really different from the left ?

Authors:  Lars Grosse-Wortmann; Christopher K Macgowan; Logi Vidarsson; Shi-Joon Yoo
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  10 in total

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