Literature DB >> 15878269

A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes.

Sharon N Bisaha1, Mary F Malley, Andrew Pudzianowski, Hossain Monshizadegan, Paulina Wang, Cort S Madsen, Jack Z Gougoutas, Philip D Stein.   

Abstract

The preferred absolute configuration of two series of F(1)F(0)-ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents the same 'triaryl' pharmacophore to the enzyme binding site.

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Year:  2005        PMID: 15878269     DOI: 10.1016/j.bmcl.2005.03.115

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  A convergent, scalable and stereoselective synthesis of azole CYP51 inhibitors.

Authors:  Galina Lepesheva; Plamen Christov; Gary A Sulikowski; Kwangho Kim
Journal:  Tetrahedron Lett       Date:  2017-09-25       Impact factor: 2.415

2.  Imaza-lil: 1-[2-(2,4-dichloro-phen-yl)-2-(prop-2-en-yloxy)eth-yl]-1H-imidazole.

Authors:  Sanghun Cheon; Yong Woon Shin; Ki-Min Park; Jineun Kim; Tae Ho Kim
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-05-20
  2 in total

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