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Literature DB >> 15877138

Dendrimeric Gd(III) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion.

Jakub Rudovsky¹, Petr Hermann, Mauro Botta, Silvio Aime, Ivan Lukes.

Abstract

A marked increase of relaxivity has been observed upon rigidifying the internal frame of Gd-containing PAMAM dendrimers: the effect has been attained by either protonation of the dendrimer or by forming supramolecular adducts with cationic polyaminoacids.

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 15877138 DOI： 10.1039/b418712a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

12 in total

1. Strategies for the preparation of bifunctional gadolinium(III) chelators.

Authors: Luca Frullano; Peter Caravan
Journal: Curr Org Synth Date: 2011-08-01 Impact factor: 1.975

Review 2. Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics.

Authors: Aaron Joseph L Villaraza; Ambika Bumb; Martin W Brechbiel
Journal: Chem Rev Date: 2010-05-12 Impact factor: 60.622

3. A modular system for the synthesis of multiplexed magnetic resonance probes.

Authors: Daniel J Mastarone; Victoria S R Harrison; Amanda L Eckermann; Giacomo Parigi; Claudio Luchinat; Thomas J Meade
Journal: J Am Chem Soc Date: 2011-03-17 Impact factor: 15.419

4. Metal Chelating Crosslinkers Form Nanogels with High Chelation Stability.

Authors: Jacques Lux; Minnie Chan; Luce Vander Elst; Eric Schopf; Enas Mahmoud; Sophie Laurent; Adah Almutairi
Journal: J Mater Chem B Date: 2013-12-14 Impact factor: 6.331

Review 5. Engineering Gd-loaded nanoparticles to enhance MRI sensitivity via T(1) shortening.

Authors: Michael A Bruckman; Xin Yu; Nicole F Steinmetz
Journal: Nanotechnology Date: 2013-10-24 Impact factor: 3.874

6. A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity.

Authors: Kuan-Ju Chen; Stephanie M Wolahan; Hao Wang; Chao-Hsiung Hsu; Hsing-Wei Chang; Armando Durazo; Lian-Pin Hwang; Mitch A Garcia; Ziyue K Jiang; Lily Wu; Yung-Ya Lin; Hsian-Rong Tseng
Journal: Biomaterials Date: 2010-12-16 Impact factor: 12.479

Dendrimeric Gd(III) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion.

1. Strategies for the preparation of bifunctional gadolinium(III) chelators.

Review 2. Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics.

3. A modular system for the synthesis of multiplexed magnetic resonance probes.

4. Metal Chelating Crosslinkers Form Nanogels with High Chelation Stability.

Review 5. Engineering Gd-loaded nanoparticles to enhance MRI sensitivity via T(1) shortening.

6. A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity.

7. An extracellular MRI polymeric contrast agent that degrades at physiological pH.

Review 8. Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo.

Review 9. Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation.

10. Nanoassembled capsules as delivery vehicles for large payloads of high relaxivity Gd3+ agents.