Literature DB >> 15877132

A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes.

Matt Cheeseman1, Fred J P Feuillet, Andrew L Johnson, Steven D Bull.   

Abstract

A new way of combining chiral auxiliaries and substrate-directable reactions for asymmetric synthesis is described that employs a three-step sequence of aldol-cyclopropanation-retro-aldol reactions for the stereoselective synthesis of enantiopure cyclopropane carboxaldehydes.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 15877132     DOI: 10.1039/b501847a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Solid-phase asymmetric synthesis using a polymer-supported chiral Evans'-type oxazolidin-2-one.

Authors:  Rachel Green; Jennifer Peed; James E Taylor; Richard A R Blackburn; Steven D Bull
Journal:  Nat Protoc       Date:  2013-09-12       Impact factor: 13.491

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.