| Literature DB >> 15876537 |
Dongliang Liu1, Jianjun Hu, Weihong Qiao, Zongshi Li, Shubiao Zhang, Lvbo Cheng.
Abstract
Series of lipids 1a-d and 2a,b, with carbamate linkages between hydrocarbon chains and ammonium or tertiary amine head, which were pH sensitive, were synthesized for liposome-mediated gene delivery. The variable length of carbon chains and quaternary ammonium or neutral tertiary amine heads allowed to find the structure-function relationship of how these factors affect cationic lipids on gene delivery performance.Entities:
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Year: 2005 PMID： 15876537 DOI： 10.1016/j.bmcl.2005.04.010
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823