Literature DB >> 1587528

Cytogenetic studies in motile sperm from normal men.

J Benet1, A Genescà, J Navarro, J Egozcue, C Templado.   

Abstract

Most studies on human sperm chromosomes from normal men involve the heterologous fertilization of zona free hamster eggs by unselected human sperm. In this work, we have performed cytogenetic studies of highly motile sperm, selected by a swim-up method. A total of 505 motile human sperm complements from three normal donors was analysed. The total frequency of sperm with chromosomal abnormalities (10.9%; 6.9% structural aberrations and 4.0% aneuploidy) and the sex ratio (50.4% X:49.6% Y) were similar to those obtained from whole semen samples. Our results indicate that the selection of motile sperm does not imply chromosomal selection.

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Year:  1992        PMID： 1587528     DOI： 10.1007/bf00217119

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  21 in total

1.  Chromosome constitution of highly motile mouse sperm.

Authors:  A Estop; V Catala; J Santalo
Journal:  Mol Reprod Dev       Date:  1990-10       Impact factor: 2.609

2.  Expression of a possible constitutional "hot spot" in sperm chromosomes of a patient treated for Wilms' tumor.

Authors:  A Genescà; R Miró; M R Caballin; J Benet; J Navarro; C Templado; X Bonfill; J Egozcue
Journal:  Cancer Genet Cytogenet       Date:  1987-11

3.  Fragile sites induced by FUdR, caffeine, and aphidicolin. Their frequency, distribution, and analysis.

Authors:  P N Rao; N A Heerema; C G Palmer
Journal:  Hum Genet       Date:  1988-01       Impact factor: 4.132

4.  Improvement of sperm quality in abnormal semen samples using a modified swim-up procedure.

Authors:  P Andolz; M A Bielsa; A Genesca; J Benet; J Egozcue
Journal:  Hum Reprod       Date:  1987-02       Impact factor: 6.918

5.  An improved, efficient method for analyzing human sperm chromosomes using zona-free hamster ova.

Authors:  Y Kamiguchi; K Mikamo
Journal:  Am J Hum Genet       Date:  1986-05       Impact factor: 11.025

6.  Chromosome analysis of human sperm. I. First results with a modified method.

Authors:  J Jenderny; G Röhrborn
Journal:  Hum Genet       Date:  1987-08       Impact factor: 4.132

7.  The frequency of aneuploidy among individual chromosomes in 6,821 human sperm chromosome complements.

Authors:  R H Martin; A Rademaker
Journal:  Cytogenet Cell Genet       Date:  1990

8.  Chromosome abnormalities in human spermatozoa after albumin or TEST-Yolk capacitation.

Authors:  J Benet; J Navarro; A Genescà; J Egozcue; C Templado
Journal:  Hum Reprod       Date:  1991-03       Impact factor: 6.918

9.  Chromosomes of human sperm: variability among normal individuals.

Authors:  B Brandriff; L Gordon; L Ashworth; G Watchmaker; D Moore; A J Wyrobek; A V Carrano
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

10.  Expression of folate-sensitive fragile sites in lymphocyte chromosomes.

Authors:  C Fuster; R Miró; C Templado; L Barrios; J Egozcue
Journal:  Hum Genet       Date:  1989-02       Impact factor: 4.132
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  5 in total

Review 1.  Cytogenetics of human spermatozoa: what about the reproductive relevance of structural chromosome aberrations?

Authors:  B E Rosenbusch
Journal:  J Assist Reprod Genet       Date:  1995-07       Impact factor: 3.412

2.  Multicolor FISH analysis of chromosomal breaks, duplications, deletions, and numerical abnormalities in the sperm of healthy men.

Authors:  E D Sloter; X Lowe; D H Moore II; J Nath; A J Wyrobek
Journal:  Am J Hum Genet       Date:  2000-08-28       Impact factor: 11.025

3.  Cytogenetics of human spermatozoa. The frequency of various chromosome aberrations and their relationship to clinical and biological parameters.

Authors:  B Rosenbusch; K Sterzik
Journal:  Arch Gynecol Obstet       Date:  1994       Impact factor: 2.344

4.  An analysis of human sperm chromosome breakpoints.

Authors:  A M Estop; C Márquez; S Munné; J Navarro; K Cieply; V Van Kirk; M R Martorell; J Benet; C Templado
Journal:  Am J Hum Genet       Date:  1995-02       Impact factor: 11.025

Review 5.  New Biological Insights on X and Y Chromosome-Bearing Spermatozoa.

Authors:  Md Saidur Rahman; Myung-Geol Pang
Journal:  Front Cell Dev Biol       Date:  2020-01-21
  5 in total

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