Literature DB >> 1587353

Murine ST2 gene is a member of the primary response gene family induced by growth factors.

K Yanagisawa1, T Tsukamoto, T Takagi, S Tominaga.   

Abstract

The murine ST2 gene, which encodes a protein remarkably similar to the extracellular portion of murine interleukin 1 receptor types 1 and 2, is expressed in growth-stimulated BALB/c-3T3 cells in the presence of 50 micrograms/ml of cycloheximide. The treatment with 1,000 U/ml of purified native murine beta-interferon superinduced, rather than suppressed, the ST2 mRNA expression as in the cases of c-myc and JE mRNAs. These results suggested that the murine ST2 gene belongs to the family of primary response genes induced by growth factors. Furthermore, a longer ST2-related mRNA was found in BALB/c-3T3 cells that were stimulated to proliferate in the presence of cycloheximide.

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Year:  1992        PMID： 1587353     DOI： 10.1016/0014-5793(92)80282-l

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

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4.  T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses.

Authors:  M J Townsend; P G Fallon; D J Matthews; H E Jolin; A N McKenzie
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7.  Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye.

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8.  Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis.

Authors:  Jiri F P Wagenaar; M Hussein Gasem; Marga G A Goris; Mariska Leeflang; Rudy A Hartskeerl; Tom van der Poll; Cornelis van 't Veer; Eric C M van Gorp
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9.  Increased IL-33 in synovial fluid and paired serum is associated with disease activity and autoantibodies in rheumatoid arthritis.

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  9 in total

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