Literature DB >> 15872323

Percutaneous radiofrequency ablation of renal tumors: technique, complications, and outcomes.

Kamran Ahrar1, Surena Matin, Christopher G Wood, Michael J Wallace, Sanjay Gupta, David C Madoff, Sujaya Rao, Nizar M Tannir, Eric Jonasch, Louis L Pisters, Marc A Rozner, Debra L Kennamer, Marshall E Hicks.   

Abstract

PURPOSE: To report the safety, technical success, and effectiveness of percutaneous radiofrequency (RF) ablation for renal tumors.
MATERIALS AND METHODS: The authors retrospectively reviewed the medical records and imaging studies of 29 consecutive patients (18 men, 11 women; mean age, 65 +/- 2.62 years) with 30 renal tumors (mean diameter, 3.5 +/- 0.24 cm) who underwent percutaneous RF ablation at their institution from September 2001 to March 2004. All procedures were performed with computed tomography guidance with general anesthesia, and all patients were admitted to the hospital for overnight observation. Technical success, complications, and their management were recorded. Technique effectiveness was assessed by imaging and clinical follow up.
RESULTS: Overall, 88 overlapping ablations were performed (mean, 2.6 +/- 0.16 ablations per tumor per session) in 34 sessions. There were four major complications (12%). Three patients had gross hematuria and urinary obstruction, all were successfully treated. One patient had persistent anterior abdominal wall weakness. There were also two minor complications (6%) without significant clinical sequelae. One patient had gross hematuria which resolved spontaneously, another patient had transient paresthesia of the anterior abdominal wall. There were no significant changes in renal function after RF ablation. The intent of RF ablation was eradication of the primary tumor in 27 patients and treatment of gross hematuria in the other two. Technical success was achieved in all cases. Follow-up images were available for 26 patients. The primary tumor was completely ablated in 23 of 24 patients (96%) in whom eradication of the primary tumor was attempted (follow up period: mean, 10 months, median 7 months). The two patients treated for hematuria remained asymptomatic for 6 and 27 months each.
CONCLUSION: Percutaneous RF ablation for renal tumors is safe and well tolerated. High technical success rates are expected. Early reports of the technique's effectiveness are promising.

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Year:  2005        PMID: 15872323     DOI: 10.1097/01.RVI.0000153589.10908.5F

Source DB:  PubMed          Journal:  J Vasc Interv Radiol        ISSN: 1051-0443            Impact factor:   3.464


  20 in total

Review 1.  Results of radiofrequency kidney tumor ablation: renal function preservation and oncologic efficacy.

Authors:  Nelson Salas; Rajan Ramanathan; Scott Dummett; Raymond J Leveillee
Journal:  World J Urol       Date:  2010-05-09       Impact factor: 4.226

2.  Thermo-sensitive hydrogel for preventing bowel injury in percutaneous renal radiofrequency ablation.

Authors:  Xin Wang; Xiaozhi Zhao; Tingsheng Lin; Hongqian Guo
Journal:  Int Urol Nephrol       Date:  2016-07-09       Impact factor: 2.370

3.  Complications of radiofrequency ablation of neoplasms.

Authors:  Albert A Nemcek
Journal:  Semin Intervent Radiol       Date:  2006-06       Impact factor: 1.513

Review 4.  Laparoscopic and image-guided radiofrequency ablation of renal tumors: patient selection and outcomes.

Authors:  Scott M Castle; Vladislav Gorbatiy; Obi Ekwenna; Raymond J Leveillee
Journal:  Curr Urol Rep       Date:  2011-04       Impact factor: 3.092

5.  Complications of radiofrequency ablation of hepatic, pulmonary, and renal neoplasms.

Authors:  Matthew J Howenstein; Kent T Sato
Journal:  Semin Intervent Radiol       Date:  2010-09       Impact factor: 1.513

6.  Cryoablation or radiofrequency ablation of the small renal mass : a meta-analysis.

Authors:  David A Kunkle; Robert G Uzzo
Journal:  Cancer       Date:  2008-11-15       Impact factor: 6.860

7.  Radiofrequency ablation for the treatment of renal cell carcinoma: initial experience.

Authors:  Fumihiko Watanabe; Tsutomu Kawasaki; Yuhsuke Hotaka; Mitsutomi Ishiyama; Sohkun Fuwa; Mikio Nagata; Yukihisa Saida
Journal:  Radiat Med       Date:  2008-01-31

Review 8.  Ablative therapies for small renal tumours.

Authors:  Arturo Castro; Lawrence C Jenkins; Nelson Salas; Gideon Lorber; Raymond J Leveillee
Journal:  Nat Rev Urol       Date:  2013-04-23       Impact factor: 14.432

Review 9.  Role of combined embolization and ablation in management of renal masses.

Authors:  Ronald S Winokur; Bradley B Pua; David C Madoff
Journal:  Semin Intervent Radiol       Date:  2014-03       Impact factor: 1.513

Review 10.  Percutaneous ablation for small renal masses-imaging follow-up.

Authors:  Jason D Iannuccilli; David J Grand; Damian E Dupuy; William W Mayo-Smith
Journal:  Semin Intervent Radiol       Date:  2014-03       Impact factor: 1.513

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