| Literature DB >> 15872301 |
Maria José Linares1, Francisco Solís, Manuel Casal.
Abstract
A total of 104 Prototheca wickerhamii isolates and two control strains were tested for susceptibility to voriconazole using the Sensititre YeastOne colorimetric antifungal plate and NCCLS reference method. Voriconazole was highly active against all isolates, with an MIC at which 90% of isolates were inhibited of < or = 0.5 microg/ml. Comparison of MICs obtained with the Sensititre product and the NCCLS method demonstrated agreement (100% +/- 2 log2 dilutions) between the two methods. Voriconazole may offer an option for the treatment of Prototheca sp. infections, and its efficacy should be established through clinical experience.Entities:
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Year: 2005 PMID: 15872301 PMCID: PMC1153790 DOI: 10.1128/JCM.43.5.2520-2522.2005
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948