Literature DB >> 15871607

Oncological and functional results of CO2 laser cordectomy.

M Policarpo1, P Aluffi, F Brovelli, G Borello, F Pia.   

Abstract

Laser surgery represents the evolution of endoscopic surgery and, as far as concerns treatment of laryngeal tumours, CO2 laser cordectomy is considered a valid alternative to conventional surgery (laryngofissure cordectomy) and to exclusive radiotherapy for glottic carcinomas, classified as T1a, T1b and T2. The present report focuses on personal experience with CO2 laser cordectomy over the last 11 years, evaluating oncological and functional results. Between October 1990 and December 2001, micro-laryngoscopy has been performed with CO, laser, in 606 cases (benign and malignant lesions), of which 150 laser cordectomies, at the ORL Department, Eastern Piedmont University of Novara. An analysis is made of 63 patients (mean age 64.3 years) who underwent laser cordectomy for glottic carcinoma, observed at follow-up for at least 3 years. Vocal function has been studied on a sample of 20 patients. Of those who underwent CO2 laser cordectomy for T1a and T1s, 95.8% were disease free after a minimum of 3 years follow-up. Video-larynx-stroboscopic test highlighted the presence of a "satisfying" fibrous neocord in cases treated with Type III cordectomy. The speech compensation was of the "cord-neocordal" type (35%), false cordal (40%) and with arytenoideus hyperadduction (25%). The electro-acoustical analysis of the voice highlighted a "serious dysphonia" compatible with Type IV cases according to Yanagihara (70%) and moderate-severe dysphonia (30%). Mean values of vocal parameters were 5.8% for Jitter, 12.2% for Shimmer, 0.34 for NHR. CO2 laser cordectomy is first choice treatment for T1a glottic carcinoma, offering intra- and post-operative advantages: reduced traumatism, lack of tracheostomy, low bleeding, fast functional recovery (deglutition and speech), brief hospital stay, and low management costs. Dysphonia resulting from treatment, characterised by breathed voice, allows the patient to lead a normal life.

Entities:  

Mesh:

Year:  2004        PMID: 15871607

Source DB:  PubMed          Journal:  Acta Otorhinolaryngol Ital        ISSN: 0392-100X            Impact factor:   2.124


  8 in total

1.  CO₂ laser cordectomy for T1-T2 glottic cancer: oncological and functional long-term results.

Authors:  Giulia Bertino; Giulia Degiorgi; Carmine Tinelli; Salvatore Cacciola; Antonio Occhini; Marco Benazzo
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-04-21       Impact factor: 2.503

2.  Thyroarytenoid muscle invasion in T1 glottic carcinoma.

Authors:  B Pittore; H Ismail-Koch; A Davis; G Parodo; G P Ledda; P A Brennan; R Puxeddu
Journal:  Eur Arch Otorhinolaryngol       Date:  2009-03-13       Impact factor: 2.503

3.  Voice outcomes after laser surgery vs. radiotherapy of early glottic carcinoma: a meta-analysis.

Authors:  Guangyuan Du; Chuan Liu; Wenbin Yu; Juan Li; Wei Li; Chengyuan Wang; Jiang Zhu
Journal:  Int J Clin Exp Med       Date:  2015-10-15

4.  Treatment with laser CO2 cordectomy and clinical implications in management of mild and moderate laryngeal precancerosis.

Authors:  A Minni; M Barbaro; G Rispoli; F Diaferia; D Bernardeschi; R Filipo
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-10-26       Impact factor: 2.503

5.  Laser endoscopic microsurgery of laryngeal cancers.

Authors:  Sereme Moustapha; Dassonville Olivier; Bozec Alexandre; Gilles Poissonnet
Journal:  Int Arch Otorhinolaryngol       Date:  2013-11-14

6.  Evaluating Post-Radiotherapy Laryngeal Function with Laryngeal Videostroboscopy in Early Stage Glottic Cancer.

Authors:  Ariel E Marciscano; Vivek Charu; Heather M Starmer; Simon R Best; Harry Quon; Alexander T Hillel; Lee M Akst; Ana P Kiess
Journal:  Front Oncol       Date:  2017-06-12       Impact factor: 6.244

Review 7.  Voice quality after transoral CO2 laser microsurgery (TOLMS): systematic review of literature.

Authors:  Andrea Colizza; Massimo Ralli; Chiara D'Elia; Antonio Greco; Marco de Vincentiis
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-05-03       Impact factor: 3.236

8.  Oncological and functional outcome after surgical treatment of early glottic carcinoma without anterior commissure involvement.

Authors:  Jovica Milovanovic; Ana Jotic; Vojko Djukic; Bojan Pavlovic; Aleksandar Trivic; Sanja Krejovic-Trivic; Andjela Milovanovic; Aleksandar Milovanovic; Vera Artiko; Bojan Banko
Journal:  Biomed Res Int       Date:  2014-06-02       Impact factor: 3.411

  8 in total

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