| Literature DB >> 15869038 |
Abstract
Glycyrrhetinic acid, the active constituent of liquorice, inhibits renal IIbeta-hydroxysteroid dehydrogenase. This allows cortisol to stimulate mineralocorticoid receptors, which can result in hypertension and hypokalaemia. Treatment options are based on pathophysiological understanding.Entities:
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Year: 2005 PMID: 15869038
Source DB: PubMed Journal: Neth J Med ISSN: 0300-2977 Impact factor: 1.422