BACKGROUND: Solitary plasmacytoma localised to bone or soft tissue without myeloma. AIM: Clinical features and survival was analysed in patients from Central Anatolia. METHODS: Twenty-three solitary plasmacytoma (18 male, 5 female) were evaluated retrospectively. Median age was 58 years (46-72). The major localisation was vertebral column. RESULTS: All patients but one (larynx) had surgical resection and 21 patients received radiotherapy postoperatively. Multiple myeloma developed in eight patients (35%) and local relapse was detected in one patient. Eight patients died, causes of death were multiple myeloma progression in six patients, local relapse of intracranial plasmacytoma in one patient and cranial trauma in one patient who was in complete remission. Three and 5 years progression free survival were 45.6% and 22.8% respectively and overall survivals were 54.4% and 27.2% respectively. CONCLUSION: Solitary plasmacytoma cases should be followed carefully regarding local relapse and progression to myeloma.
BACKGROUND:Solitary plasmacytoma localised to bone or soft tissue without myeloma. AIM: Clinical features and survival was analysed in patients from Central Anatolia. METHODS: Twenty-three solitary plasmacytoma (18 male, 5 female) were evaluated retrospectively. Median age was 58 years (46-72). The major localisation was vertebral column. RESULTS: All patients but one (larynx) had surgical resection and 21 patients received radiotherapy postoperatively. Multiple myeloma developed in eight patients (35%) and local relapse was detected in one patient. Eight patients died, causes of death were multiple myeloma progression in six patients, local relapse of intracranial plasmacytoma in one patient and cranial trauma in one patient who was in complete remission. Three and 5 years progression free survival were 45.6% and 22.8% respectively and overall survivals were 54.4% and 27.2% respectively. CONCLUSION:Solitary plasmacytoma cases should be followed carefully regarding local relapse and progression to myeloma.
Authors: Richard Soutar; Helen Lucraft; Graham Jackson; Anthony Reece; Jenny Bird; Eric Low; Diana Samson Journal: Br J Haematol Date: 2004-03 Impact factor: 6.998
Authors: P Galieni; M Cavo; G Avvisati; A Pulsoni; R Falbo; M A Bonelli; D Russo; M T Petrucci; A Bucalossi; S Tura Journal: Ann Oncol Date: 1995-09 Impact factor: 32.976
Authors: Elżbieta Szczepanek; Joanna Drozd-Sokołowska; Jacek Sokołowski; Anna Rzepakowska; Arkadiusz Moskwa; Jakub Pachla; Jakub Grzybowski; Katarzyna Woźnica; Kazimierz Niemczyk; Krzysztof Jamroziak Journal: J Clin Med Date: 2022-07-28 Impact factor: 4.964