| Literature DB >> 15866155 |
Elona Kolpakova1, Bjorn R Olsen.
Abstract
Three exciting papers in this issue of Developmental Cell provide new insights into the regulation of chondrocytic, osteoblastic, and osteoclastic differentiation during skeletal development and postnatal growth. The studies demonstrate that Wnt/beta-catenin signaling represents both a mechanism in mesenchymal precursor cells for selecting between chondrocytic and osteoblastic fates as well as a mechanism in osteoblasts for stimulating the production of an inhibitor of osteoclast formation.Entities:
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Year: 2005 PMID: 15866155 DOI: 10.1016/j.devcel.2005.04.008
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270