Literature DB >> 15863686

The book of life.

P Copland1.   

Abstract

It has recently been suggested that the practice of bioethics in the area of biology and genetics has been hampered by the lack of an accurate and appropriate metaphor. Beginning with previous metaphors that have compared the genome with a static blueprint or "book of life", I develop a dynamic metaphor that is compatible with our present understanding of the role of genetics in biology. The resulting metaphor is not only an accurate representation of current biology but of particular use to bioethicists and non-biologists in general.

Keywords:  Biomedical and Behavioral Research; Genetics and Reproduction

Mesh:

Year:  2005        PMID: 15863686      PMCID: PMC1734152          DOI: 10.1136/jme.2003.005173

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  7 in total

1.  The genetic program of hematopoietic stem cells.

Authors:  R L Phillips; R E Ernst; B Brunk; N Ivanova; M A Mahan; J K Deanehan; K A Moore; G C Overton; I R Lemischka
Journal:  Science       Date:  2000-06-02       Impact factor: 47.728

2.  Cell differentiation by mechanical stress.

Authors:  Gregory H Altman; Rebecca L Horan; Ivan Martin; Jian Farhadi; Peter R H Stark; Vladimir Volloch; John C Richmond; Gordana Vunjak-Novakovic; David L Kaplan
Journal:  FASEB J       Date:  2001-12-28       Impact factor: 5.191

3.  Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model.

Authors:  Lars M Bjorklund; Rosario Sánchez-Pernaute; Sangmi Chung; Therese Andersson; Iris Yin Ching Chen; Kevin St P McNaught; Anna-Liisa Brownell; Bruce G Jenkins; Claes Wahlestedt; Kwang-Soo Kim; Ole Isacson
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-08       Impact factor: 11.205

4.  The double helix 50 years on: models, metaphors, and reductionism.

Authors:  R E Ashcroft
Journal:  J Med Ethics       Date:  2003-04       Impact factor: 2.903

5.  The bioethical structure of a human being.

Authors:  Paul Copland; Grant Gillett
Journal:  J Appl Philos       Date:  2003

6.  What exactly is an exact copy? And why it matters when trying to ban human reproductive cloning in Australia.

Authors:  B Gogarty
Journal:  J Med Ethics       Date:  2003-04       Impact factor: 2.903

7.  Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: enlarging genus Homo.

Authors:  Derek E Wildman; Monica Uddin; Guozhen Liu; Lawrence I Grossman; Morris Goodman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-23       Impact factor: 11.205

  7 in total
  1 in total

1.  "Here comes Bio-me": An analysis of a biobank campaign targeted at children.

Authors:  Karoliina Snell; Heta Tarkkala
Journal:  Public Underst Sci       Date:  2021-06-19
  1 in total

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