Literature DB >> 15863312

Design, new synthesis, and calcilytic activity of substituted 3H-pyrimidin-4-ones.

Irina Shcherbakova1, Guangfei Huang, Otto J Geoffroy, Satheesh K Nair, Krzysztof Swierczek, Manuel F Balandrin, John Fox, William L Heaton, Rebecca L Conklin.   

Abstract

Design, new synthesis, structure-activity relationship studies and calcium receptor antagonist (calcilytic) properties of novel 3H-pyrimidin-4-ones are described.

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Year:  2005        PMID: 15863312     DOI: 10.1016/j.bmcl.2005.03.054

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

Review 1.  International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function.

Authors:  Katie Leach; Fadil M Hannan; Tracy M Josephs; Andrew N Keller; Thor C Møller; Donald T Ward; Enikö Kallay; Rebecca S Mason; Rajesh V Thakker; Daniela Riccardi; Arthur D Conigrave; Hans Bräuner-Osborne
Journal:  Pharmacol Rev       Date:  2020-07       Impact factor: 25.468

  1 in total

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