Literature DB >> 15862830

The 1,25D3-MARRS protein: contribution to steroid stimulated calcium uptake in chicks and rats.

Ilka Nemere1.   

Abstract

There are currently two main candidates for the membrane receptor for 1,25(OH)2D3: the 1,25D3-MARRS protein/ERp57; and the classical VDR. The 1,25D3-MARRS protein is essential for hormone-stimulated phosphate and calcium uptake in chick intestinal cells, whereas the VDR is not. The 1,25D3-MARRS protein also shows a high degree of correlation with growth periods in which bone is rapidly formed, whereas the VDR does not. However, in rat enterocytes, both the 1,25D3-MARRS protein and the VDR play a role in the rapid, steroid-mediated uptake of phosphate or calcium. Therefore, the theory that alternate binding sites on the VDR for various analogs account for all membrane-initiated phenomena, is incorrect.

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Year:  2005        PMID： 15862830     DOI： 10.1016/j.steroids.2005.02.005

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  7 in total

1.  Intestinal cell calcium uptake and the targeted knockout of the 1,25D3-MARRS (membrane-associated, rapid response steroid-binding) receptor/PDIA3/Erp57.

Authors:  Ilka Nemere; Natalio Garbi; Gunter J Hämmerling; Ramesh C Khanal
Journal:  J Biol Chem       Date:  2010-08-03       Impact factor: 5.157

2.  Tumor necrosis factor-α treatment of HepG2 cells mobilizes a cytoplasmic pool of ERp57/1,25D₃-MARRS to the nucleus.

Authors:  Brian J Grindel; Benjamin Rohe; Susan E Safford; Joseph J Bennett; Mary C Farach-Carson
Journal:  J Cell Biochem       Date:  2011-09       Impact factor: 4.429

3.  Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci.

Authors:  Nichole T Huffman; J Andrew Keightley; Cui Chaoying; Ronald J Midura; Dinah Lovitch; Patricia A Veno; Sarah L Dallas; Jeff P Gorski
Journal:  J Biol Chem       Date:  2007-07-05       Impact factor: 5.157

4.  Impaired bone formation in Pdia3 deficient mice.

Authors:  Yun Wang; Alexandr Nizkorodov; Kelsie Riemenschneider; Christopher S D Lee; Rene Olivares-Navarrete; Zvi Schwartz; Barbara D Boyan
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

5.  Cellular and animal models for high-throughput screening of therapeutic agents for the treatment of the diseases of the elderly in general and Alzheimer's disease in particular(†).

Authors:  Jordan L Holtzman
Journal:  Front Pharmacol       Date:  2013-05-13       Impact factor: 5.810

Review 6.  The Use of 1α,25-Dihydroxyvitamin D₃ as an Anticancer Agent.

Authors:  Ewa Marcinkowska; Graham R Wallace; Geoffrey Brown
Journal:  Int J Mol Sci       Date:  2016-05-13       Impact factor: 5.923

7.  Expression of protein disulfide isomerase A3 precursor in colorectal cancer.

Authors:  Zhaowei Yang; Juan Liu; Qinghong Shi; Yang Chao; Yanqing Di; Jing Sun; Jiebing Zhang; Lihong Huang; Honghua Guo; Chengyan He
Journal:  Onco Targets Ther       Date:  2018-07-19       Impact factor: 4.147
  7 in total

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