Literature DB >> 15860425

Metabolon formation and metabolic channeling in the biosynthesis of plant natural products.

Kirsten Jørgensen1, Anne Vinther Rasmussen, Marc Morant, Allan Holm Nielsen, Nanna Bjarnholt, Mika Zagrobelny, Søren Bak, Birger Lindberg Møller.   

Abstract

Metabolon formation and metabolic channeling in plant secondary metabolism enable plants to effectively synthesize specific natural products and to avoid metabolic interference. Channeling can involve different cell types, take advantage of compartmentalization within the same cell or proceed directly within a metabolon. New experimental approaches document the importance of channeling in the synthesis of isoprenoids, alkaloids, phenylpropanoids, flavonoids and cyanogenic glucosides. Metabolon formation and metabolic channeling in natural-product synthesis facilitate attempts to genetically engineer new pathways into plants to improve their content of valuable natural products. They also offer the opportunity to introduce new traits by genetic engineering to produce plant cultivars that adhere to the principle of substantial equivalence.

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Year:  2005        PMID: 15860425     DOI: 10.1016/j.pbi.2005.03.014

Source DB:  PubMed          Journal:  Curr Opin Plant Biol        ISSN: 1369-5266            Impact factor:   7.834


  143 in total

1.  Biosynthesis of proanthocyanidins in white clover flowers: cross talk within the flavonoid pathway.

Authors:  Shamila Weerakoon Abeynayake; Stephen Panter; Ross Chapman; Tracie Webster; Simone Rochfort; Aidyn Mouradov; German Spangenberg
Journal:  Plant Physiol       Date:  2011-12-13       Impact factor: 8.340

2.  Megadalton complexes in the chloroplast stroma of Arabidopsis thaliana characterized by size exclusion chromatography, mass spectrometry, and hierarchical clustering.

Authors:  Paul Dominic B Olinares; Lalit Ponnala; Klaas J van Wijk
Journal:  Mol Cell Proteomics       Date:  2010-04-26       Impact factor: 5.911

3.  Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone.

Authors:  Daniel Cook; Agnes M Rimando; Thomas E Clemente; Joachim Schröder; Franck E Dayan; N P Dhammika Nanayakkara; Zhiqiang Pan; Brice P Noonan; Mark Fishbein; Ikuro Abe; Stephen O Duke; Scott R Baerson
Journal:  Plant Cell       Date:  2010-03-26       Impact factor: 11.277

4.  Expression and tissue and subcellular localization of anthocyanidin synthase (ANS) in grapevine.

Authors:  Huiling Wang; Wei Wang; Hui Li; Ping Zhang; Jicheng Zhan; Weidong Huang
Journal:  Protoplasma       Date:  2010-06-30       Impact factor: 3.356

5.  Cytochrome b 5 Is an Obligate Electron Shuttle Protein for Syringyl Lignin Biosynthesis in Arabidopsis.

Authors:  Mingyue Gou; Xiaoman Yang; Yunjun Zhao; Xiuzhi Ran; Yanzhai Song; Chang-Jun Liu
Journal:  Plant Cell       Date:  2019-04-08       Impact factor: 11.277

6.  Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme.

Authors:  Kirsten Jørgensen; Anne Vinther Morant; Marc Morant; Niels Bjerg Jensen; Carl Erik Olsen; Rubini Kannangara; Mohammed Saddik Motawia; Birger Lindberg Møller; Søren Bak
Journal:  Plant Physiol       Date:  2010-11-02       Impact factor: 8.340

Review 7.  Biosynthesis of terpene compounds using the non-model yeast Yarrowia lipolytica: grand challenges and a few perspectives.

Authors:  Alyssa M Worland; Jeffrey J Czajka; Yanran Li; Yechun Wang; Yinjie J Tang; Wei Wen Su
Journal:  Curr Opin Biotechnol       Date:  2020-04-13       Impact factor: 9.740

8.  Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity.

Authors:  Miguel Cervantes-Cervantes; Cynthia E Gallagher; Changfu Zhu; Eleanore T Wurtzel
Journal:  Plant Physiol       Date:  2006-03-31       Impact factor: 8.340

9.  Glycolytic enzymes associate dynamically with mitochondria in response to respiratory demand and support substrate channeling.

Authors:  James W A Graham; Thomas C R Williams; Megan Morgan; Alisdair R Fernie; R George Ratcliffe; Lee J Sweetlove
Journal:  Plant Cell       Date:  2007-11-02       Impact factor: 11.277

10.  Reprogramming the phenylpropanoid metabolism in seeds of oilseed rape by suppressing the orthologs of reduced epidermal fluorescence1.

Authors:  Juliane Mittasch; Christoph Böttcher; Andrej Frolov; Dieter Strack; Carsten Milkowski
Journal:  Plant Physiol       Date:  2013-02-19       Impact factor: 8.340

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