Literature DB >> 15860368

Emerging role of the FGF system in psychiatric disorders.

Marco A Riva1, Raffaella Molteni, Francesco Bedogni, Giorgio Racagni, Fabio Fumagalli.   

Abstract

Fibroblast growth factors (FGFs) comprise several peptides that, by interacting with a family of FGF receptors, participate in brain development and contribute to neuronal repair and plasticity. Recent evidence suggests that the expression of FGFs is altered in mood disorders and can be regulated by psychotropic drugs. This provides further support to the notion that neurotrophic molecules might have a role in the etiology and treatment of mental disorders.

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Year:  2005        PMID： 15860368     DOI： 10.1016/j.tips.2005.03.001

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  15 in total

Review 1.  Fibroblast growth factors in schizophrenia.

Authors:  Afke F Terwisscha van Scheltinga; Steven C Bakker; René S Kahn
Journal:  Schizophr Bull       Date:  2009-05-08       Impact factor: 9.306

2.  A single exposure to cocaine during development elicits regionally-selective changes in basal basic Fibroblast Growth Factor (FGF-2) gene expression and alters the trophic response to a second injection.

Authors:  Giuseppe Giannotti; Lucia Caffino; Chiara Malpighi; Simona Melfi; Giorgio Racagni; Fabio Fumagalli
Journal:  Psychopharmacology (Berl)       Date:  2014-08-16       Impact factor: 4.530

3.  Expression of fibroblast growth factor-2 and brain-derived neurotrophic factor mRNA in the medial prefrontal cortex and hippocampus after uncontrollable or controllable stress.

Authors:  S T Bland; J P Tamlyn; R M Barrientos; B N Greenwood; L R Watkins; S Campeau; H E Day; S F Maier
Journal:  Neuroscience       Date:  2006-12-29       Impact factor: 3.590

Review 4.  Role of vascular endothelial growth factor in adult hippocampal neurogenesis: implications for the pathophysiology and treatment of depression.

Authors:  Neil M Fournier; Ronald S Duman
Journal:  Behav Brain Res       Date:  2011-04-22       Impact factor: 3.332

5.  Learning and memory depend on fibroblast growth factor receptor 2 functioning in hippocampus.

Authors:  Hanna E Stevens; Ginger Y Jiang; Michael L Schwartz; Flora M Vaccarino
Journal:  Biol Psychiatry       Date:  2012-04-27       Impact factor: 13.382

6.  Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

Authors:  Klementina Fon Tacer; Angie L Bookout; Xunshan Ding; Hiroshi Kurosu; George B John; Lei Wang; Regina Goetz; Moosa Mohammadi; Makoto Kuro-o; David J Mangelsdorf; Steven A Kliewer
Journal:  Mol Endocrinol       Date:  2010-07-28

7.  Region-specific effects of developmental exposure to cocaine on fibroblast growth factor-2 expression in the rat brain.

Authors:  Giuseppe Giannotti; Lucia Caffino; Francesca Mottarlini; Giorgio Racagni; Fabio Fumagalli
Journal:  Psychopharmacology (Berl)       Date:  2016-04-30       Impact factor: 4.530

8.  Stress and cocaine interact to modulate basic fibroblast growth factor (FGF-2) expression in rat brain.

Authors:  Fabio Fumagalli; Laura Di Pasquale; Lucia Caffino; Giorgio Racagni; Marco Andrea Riva
Journal:  Psychopharmacology (Berl)       Date:  2007-10-04       Impact factor: 4.530

Review 9.  Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia.

Authors:  John H Krystal; David F Tolin; Gerard Sanacora; Stacy A Castner; Graham V Williams; Deane E Aikins; Ralph E Hoffman; D Cyril D'Souza
Journal:  Drug Discov Today       Date:  2009-05-19       Impact factor: 7.851

10.  An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS).

Authors:  Salvador Harguindey; Gorka Orive; Ramón Cacabelos; Enrique Meléndez Hevia; Ramón Díaz de Otazu; Jose Luis Arranz; Eduardo Anitua
Journal:  Neuropsychiatr Dis Treat       Date:  2008-12       Impact factor: 2.570
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