Pascal M Jabbour1, Steven G Ojemann. 1. Department of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA 19131, USA. pascal.jabbour@mail.tju.edu
Abstract
BACKGROUND: Herpes simplex encephalitis (HSE) still carries a high morbidity and mortality. REVIEW SUMMARY: The authors report a 27-year-old patient who presented with an HSE manifested by a high temperature, seizures, and headaches. His hospitalization course was complicated by a pulmonary embolism. After anticoagulation was started, the patient developed a right temporal hematoma at the same region of the abnormal signal on magnetic resonance imaging. The patient underwent a craniotomy and evacuation of the hematoma with an uneventful postoperative outcome. CONCLUSION: The safety of anticoagulation in HSE has not been raised in the literature previously, and it needs further study.
BACKGROUND: Herpes simplex encephalitis (HSE) still carries a high morbidity and mortality. REVIEW SUMMARY: The authors report a 27-year-old patient who presented with an HSE manifested by a high temperature, seizures, and headaches. His hospitalization course was complicated by a pulmonary embolism. After anticoagulation was started, the patient developed a right temporal hematoma at the same region of the abnormal signal on magnetic resonance imaging. The patient underwent a craniotomy and evacuation of the hematoma with an uneventful postoperative outcome. CONCLUSION: The safety of anticoagulation in HSE has not been raised in the literature previously, and it needs further study.