BACKGROUND: There is a dearth of information regarding the occurrence of cutaneous melanoma in a large cohort of persons with large congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi (MCMN). OBJECTIVE: The purpose of this article is to report our experience with 1008 persons having LCMN and MCMN. METHODS: Information was evaluated that was obtained from a database of persons with LCMN or MCMN voluntarily submitted by the affected persons to a nevus support group, the Nevus Network. RESULTS: Of those with garment LCMN, 2.9% developed cutaneous melanoma associated with 0.8% deaths. Of those with LCMN on the head or extremity, 0.3% developed cutaneous melanoma associated with no deaths to date. Of the small number with MCMN without a giant nevus, 6.7% developed cutaneous melanoma. LIMITATIONS: Attending physician confirmation of submitted information was unavailable. Conclusions LCMN and MCMN were associated with a low occurrence of cutaneous melanoma in our group.
BACKGROUND: There is a dearth of information regarding the occurrence of cutaneous melanoma in a large cohort of persons with large congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi (MCMN). OBJECTIVE: The purpose of this article is to report our experience with 1008 persons having LCMN and MCMN. METHODS: Information was evaluated that was obtained from a database of persons with LCMN or MCMN voluntarily submitted by the affected persons to a nevus support group, the Nevus Network. RESULTS: Of those with garment LCMN, 2.9% developed cutaneous melanoma associated with 0.8% deaths. Of those with LCMN on the head or extremity, 0.3% developed cutaneous melanoma associated with no deaths to date. Of the small number with MCMN without a giant nevus, 6.7% developed cutaneous melanoma. LIMITATIONS: Attending physician confirmation of submitted information was unavailable. Conclusions LCMN and MCMN were associated with a low occurrence of cutaneous melanoma in our group.
Authors: D Shitara; G Tell-Martí; C Badenas; M M S S Enokihara; L Alós; A B Larque; N Michalany; J A Puig-Butille; C Carrera; J Malvehy; S Puig; E Bagatin Journal: Br J Dermatol Date: 2015-06-19 Impact factor: 9.302
Authors: Klaus J Busam; Kara N Shah; Pedram Gerami; Thomas Sitzman; Achim A Jungbluth; Veronica Kinsler Journal: Am J Surg Pathol Date: 2017-03 Impact factor: 6.394
Authors: Christina Hsiao Wei; Brenda A Shoo; Daniel C Zedek; Mohammed Kashani-Sabet; Richard W Sagebiel; Stanley P L Leong Journal: BMJ Case Rep Date: 2009-02-27
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