Jeffrey S Upperman1, Robert L Sheridan. 1. Division of Pediatric Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Abstract
OBJECTIVE: The purpose of this review is to review how pediatric trauma may predispose children to sepsis. DESIGN: The information discussed in this report is derived from a recent literature review of pediatric trauma and related topics and discussion at an international consensus conference on pediatric sepsis. MEASUREMENTS AND MAIN RESULTS: There is a paucity of evidence on sepsis-related complications in pediatric trauma patients. Severe traumatic brain injury is a leading predisposing factor for sepsis complications. Excluding burn trauma, traumatically injured children without severe head injury rarely succumb to overwhelming sepsis. CONCLUSIONS: Patients with multiple traumatic injuries are frequently admitted to the intensive care unit, and because head injury is the most common ailment, unconscious patients with a combination of injuries that include head injury will regularly require mechanical ventilation and central venous access and are at risk for life-threatening nosocomial infections. Outside of pulmonary contusions, organ-specific causes of infection are infrequent.
OBJECTIVE: The purpose of this review is to review how pediatric trauma may predispose children to sepsis. DESIGN: The information discussed in this report is derived from a recent literature review of pediatric trauma and related topics and discussion at an international consensus conference on pediatric sepsis. MEASUREMENTS AND MAIN RESULTS: There is a paucity of evidence on sepsis-related complications in pediatric traumapatients. Severe traumatic brain injury is a leading predisposing factor for sepsis complications. Excluding burn trauma, traumatically injured children without severe head injury rarely succumb to overwhelming sepsis. CONCLUSIONS:Patients with multiple traumatic injuries are frequently admitted to the intensive care unit, and because head injury is the most common ailment, unconscious patients with a combination of injuries that include head injury will regularly require mechanical ventilation and central venous access and are at risk for life-threatening nosocomial infections. Outside of pulmonary contusions, organ-specific causes of infection are infrequent.
Authors: Joseph A Carcillo; J Michael Dean; Richard Holubkov; John Berger; Kathleen L Meert; Kanwaljeet J S Anand; Jerry Zimmerman; Christopher J Newth; Rick Harrison; Jeri Burr; Douglas F Willson; Carol Nicholson; Michael J Bell; Robert A Berg; Thomas P Shanley; Sabrina M Heidemann; Heidi Dalton; Tammara L Jenkins; Allan Doctor; Angie Webster Journal: Pediatr Infect Dis J Date: 2016-11 Impact factor: 2.129
Authors: Joseph A Carcillo; J Michael Dean; Richard Holubkov; John Berger; Kathleen L Meert; Kanwaljeet J S Anand; Jerry J Zimmerman; Christopher J L Newth; Rick Harrison; Jeri Burr; Douglas F Willson; Carol Nicholson; Michael J Bell; Robert A Berg; Thomas P Shanley; Sabrina M Heidemann; Heidi Dalton; Tammara L Jenkins; Allan Doctor; Angie Webster; Robert F Tamburro Journal: JPEN J Parenter Enteral Nutr Date: 2016-09-22 Impact factor: 4.016