Literature DB >> 15856964

Pregnant "DES daughters" and their offspring.

Tal Schechter, Yaron Finkelstein, Gideon Koren.   

Abstract

QUESTION: I am a 34-year-old woman in my second trimester of pregnancy. My mother took diethylstilbestrol when she was pregnant with me. Could my expected child be affected by this? ANSWER: Animal studies suggest the child could be affected, but little data on humans strongly support this. You could plan to have your child monitored for a potential, though unlikely, effect.

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Year:  2005        PMID： 15856964      PMCID： PMC1472948     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  12 in total

1.  Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women.

Authors:  A L Herbst; H Ulfelder; D C Poskanzer
Journal:  N Engl J Med       Date:  1971-04-15       Impact factor: 91.245

2.  Effects of prenatal maternal estrogen on the male urogenital system.

Authors:  S G Driscoll; S H Taylor
Journal:  Obstet Gynecol       Date:  1980-11       Impact factor: 7.661

3.  Findings in female offspring of women exposed in utero to diethylstilbestrol.

Authors:  Raymond H Kaufman; Ervin Adam
Journal:  Obstet Gynecol       Date:  2002-02       Impact factor: 7.661

4.  Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring.

Authors:  R H Kaufman; E Adam; E E Hatch; K Noller; A L Herbst; J R Palmer; R N Hoover
Journal:  Obstet Gynecol       Date:  2000-10       Impact factor: 7.661

5.  Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study.

Authors:  Helen Klip; Janneke Verloop; Jan D van Gool; Marlies E T A Koster; Curt W Burger; Flora E van Leeuwen
Journal:  Lancet       Date:  2002-03-30       Impact factor: 79.321

6.  Cancer risk in men exposed in utero to diethylstilbestrol.

Authors:  W C Strohsnitter; K L Noller; R N Hoover; S J Robboy; J R Palmer; L Titus-Ernstoff; R H Kaufman; E Adam; A L Herbst; E E Hatch
Journal:  J Natl Cancer Inst       Date:  2001-04-04       Impact factor: 13.506

Review 7.  In utero exposure to diethylstilbestrol: adverse effects on the reproductive tract and reproductive performance and male and female offspring.

Authors:  R J Stillman
Journal:  Am J Obstet Gynecol       Date:  1982-04-01       Impact factor: 8.661

8.  Structural anomalies of the cervix and vagina in women enrolled in the Diethylstilbestrol Adenosis (DESAD) Project.

Authors:  J A Jefferies; S J Robboy; P C O'Brien; E J Bergstralh; D R Labarthe; A B Barnes; K L Noller; P A Hatab; R H Kaufman; D E Townsend
Journal:  Am J Obstet Gynecol       Date:  1984-01-01       Impact factor: 8.661

9.  Genital abnormalities and abnormal semen analyses in male patients exposed to diethylstilbestrol in utero.

Authors:  E D Whitehead; E Leiter
Journal:  J Urol       Date:  1981-01       Impact factor: 7.450

10.  Ovarian carcinoma in an adolescent with transgenerational exposure to diethylstilbestrol.

Authors:  Julie Blatt; Linda Van Le; Timothy Weiner; Scott Sailer
Journal:  J Pediatr Hematol Oncol       Date:  2003-08       Impact factor: 1.289
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  1 in total

Review 1.  Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women's Health.

Authors:  Jelonia T Rumph; Victoria R Stephens; Joanie L Martin; LaKendria K Brown; Portia L Thomas; Ayorinde Cooley; Kevin G Osteen; Kaylon L Bruner-Tran
Journal:  Int J Environ Res Public Health       Date:  2022-01-23       Impact factor: 3.390
  1 in total

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