Literature DB >> 15856089

A microfluidic mixer with grooves placed on the top and bottom of the channel.

Peter B Howell1, David R Mott, Stephanie Fertig, Carolyn R Kaplan, Joel P Golden, Elaine S Oran, Frances S Ligler.   

Abstract

A new microfluidic mixer is presented consisting of a rectangular channel with grooves placed in the top and bottom. This not only increases the driving force behind the lateral flow, but allows for the formation of advection patterns that cannot be created with structures on the bottom alone. Chevrons, pointing in opposite directions on the top and bottom, are used to create a pair of vortices positioned side by side. Stripes running the width of the channel generate a pair of vertically stacked vortices. Computational fluid dynamics (CFD) simulations are used to model the behavior of the systems and provide velocity maps at cross-sections within the mixer. Experiments demonstrate the mixing that results when two segregated species enter the mixer side-by-side and pass through two cycles of the mixer (i.e., two alternating sets of four stripes and four chevrons).

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Year:  2005        PMID: 15856089     DOI: 10.1039/b418243j

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  21 in total

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5.  Dynamic reversibility of hydrodynamic focusing for recycling sheath fluid.

Authors:  Nastaran Hashemi; Peter B Howell; Jeffrey S Erickson; Joel P Golden; Frances S Ligler
Journal:  Lab Chip       Date:  2010-05-17       Impact factor: 6.799

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7.  Microfluidic flow cytometry: The role of microfabrication methodologies, performance and functional specification.

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Review 8.  Perspective on optical biosensors and integrated sensor systems.

Authors:  Frances S Ligler
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9.  Two simple and rugged designs for creating microfluidic sheath flow.

Authors:  Peter B Howell; Joel P Golden; Lisa R Hilliard; Jeffrey S Erickson; David R Mott; Frances S Ligler
Journal:  Lab Chip       Date:  2008-05-13       Impact factor: 6.799

10.  Multi-wavelength microflow cytometer using groove-generated sheath flow.

Authors:  Joel P Golden; Jason S Kim; Jeffrey S Erickson; Lisa R Hilliard; Peter B Howell; George P Anderson; Mansoor Nasir; Frances S Ligler
Journal:  Lab Chip       Date:  2009-03-31       Impact factor: 6.799

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