Literature DB >> 15855224

Dexmedetomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patients.

Krishna Baddigam1, Pierantonio Russo, Joanne Russo, Joseph D Tobias.   

Abstract

Dexmedetomidine (Precedex, Abbott Laboratories, Abbott Park, IL) is an alpha 2 adrenergic agonist that possesses a high ratio of specificity for the alpha 2 versus the alpha 1 receptor. It is currently approved for the provision of sedation during mechanical ventilation in adults. Given previous experience with clonidine for the treatment of substance withdrawal and the preliminary anecdotal experience with dexmedetomidine, it appears that dexmedetomidine may be a useful agent for treatment of substance withdrawal in the intensive care setting. The authors present their experience with the use of dexmedetomidine to control withdrawal behavior in 3 patients following cardiothoracic surgery. Previous reports regarding the use of dexmedetomidine to treat withdrawal and its potential application in this clinical arena are reviewed.

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Year:  2005        PMID： 15855224     DOI： 10.1177/0885066604273481

Source DB:  PubMed          Journal:  J Intensive Care Med        ISSN： 0885-0666            Impact factor:   3.510


  10 in total

1.  Current approaches to the recognition and treatment of alcohol withdrawal and delirium tremens: "old wine in new bottles" or "new wine in old bottles".

Authors:  Theodore A Stern; Anne F Gross; Thomas W Stern; Shamim H Nejad; Jose R Maldonado
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2010

2.  Dexmedetomidine for acute baclofen withdrawal.

Authors:  Simon Morr; Christopher M Heard; Veetai Li; Renée M Reynolds
Journal:  Neurocrit Care       Date:  2015-04       Impact factor: 3.210

Review 3.  Dexmedetomidine: applications for the pediatric patient with congenital heart disease.

Authors:  Joseph D Tobias; Punkaj Gupta; Aymen Naguib; Andrew R Yates
Journal:  Pediatr Cardiol       Date:  2011-09-10       Impact factor: 1.655

4.  Tackling agitated delirium--the tip of the iceberg.

Authors:  Valerie J Page
Journal:  Crit Care       Date:  2009-06-18       Impact factor: 9.097

Review 5.  Clinical uses of dexmedetomidine in pediatric patients.

Authors:  Hanna Phan; Milap C Nahata
Journal:  Paediatr Drugs       Date:  2008       Impact factor: 3.022

Review 6.  Dexmedetomidine: a review of applications for cardiac surgery during perioperative period.

Authors:  Xiaoyu Zhang; Xuan Zhao; Yingwei Wang
Journal:  J Anesth       Date:  2014-06-10       Impact factor: 2.078

7.  Use of dexmedetomidine for the treatment of alcohol withdrawal syndrome in critically ill patients: a retrospective case series.

Authors:  Jonas P DeMuro; David G Botros; Ela Wirkowski; Adel F Hanna
Journal:  J Anesth       Date:  2012-05-15       Impact factor: 2.078

8.  Dexmedetomidine as adjunct treatment for severe alcohol withdrawal in the ICU.

Authors:  Samuel G Rayner; Craig R Weinert; Helen Peng; Stacy Jepsen; Alain F Broccard
Journal:  Ann Intensive Care       Date:  2012-05-23       Impact factor: 6.925

9.  Dexmedetomidine use in the setting of cocaine-induced hypertensive emergency and aortic dissection: a novel indication.

Authors:  Fahad Javed; Alexandre Miguel Benjo; Kiran Reddy; Muhammad Shoaib Akram; Shahzeb Afsar Khan; Manpreet Singh Sabharwal; Girish Nadkarni; Emad F Aziz; Eyal Herzog
Journal:  Case Rep Med       Date:  2011-09-26

10.  Dexmedetomidine infusion to facilitate opioid detoxification and withdrawal in a patient with chronic opioid abuse.

Authors:  Surjya Prasad Upadhyay; Piyush Narayan Mallick; Waleed Mohamed Elmatite; Manish Jagia; Salah Taqi
Journal:  Indian J Palliat Care       Date:  2011-09
  10 in total

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