| Literature DB >> 15853296 |
Stellios Arseniyadis1, Pithani V Subhash, Alain Valleix, Suju P Mathew, Donna G Blackmond, Alain Wagner, Charles Mioskowski.
Abstract
We have described a spectacular salt effect in the kinetic resolution of (+/-)-1-phenylethylamine, which leads to an increase in reactivity, high levels of selectivity, and a complete reversal of the stereoselectivity. By tuning the reaction conditions, we were able to increase the selectivity factor of (1S,2S)-1 to s = 115.Entities:
Year: 2005 PMID： 15853296 DOI： 10.1021/ja051302+
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419