Literature DB >> 15851742

Developmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complex.

Kevin C Ess1, Christine A Kamp, Benjamin P Tu, David H Gutmann.   

Abstract

Children with tuberous sclerosis complex (TSC) harbor developmental brain abnormalities (cortical tubers) and low-grade tumors (subependymal giant cell astrocytomas [SEGAs]). Using gene expression profiling to identify neuroglial differentiation markers in Tsc1 conditional knockout mice, the authors demonstrate that giant cells of SEGAs aberrantly express similar neuroglial differentiation markers as do cortical tubers. These results suggest that both tubers and SEGAs result from related defects in progenitor cell differentiation during brain development.

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Year:  2005        PMID： 15851742     DOI： 10.1212/01.WNL.0000158653.81008.49

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  21 in total

1.  Postnatal neurogenesis generates heterotopias, olfactory micronodules and cortical infiltration following single-cell Tsc1 deletion.

Authors:  David M Feliciano; Jennifer L Quon; Tiffany Su; M Morgan Taylor; Angélique Bordey
Journal:  Hum Mol Genet       Date:  2011-11-07       Impact factor: 6.150

2.  Enhanced epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor expression in tuberous sclerosis complex.

Authors:  Whitney E Parker; Ksenia A Orlova; Gregory G Heuer; Marianna Baybis; Eleonora Aronica; Michael Frost; Michael Wong; Peter B Crino
Journal:  Am J Pathol       Date:  2010-12-23       Impact factor: 4.307

3.  Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders.

Authors:  Jasmine Jacob-Hirsch; Eran Eyal; Binyamin A Knisbacher; Jonathan Roth; Karen Cesarkas; Chen Dor; Sarit Farage-Barhom; Vered Kunik; Amos J Simon; Moran Gal; Michal Yalon; Sharon Moshitch-Moshkovitz; Rick Tearle; Shlomi Constantini; Erez Y Levanon; Ninette Amariglio; Gideon Rechavi
Journal:  Cell Res       Date:  2018-01-12       Impact factor: 25.617

Review 4.  The neurobiology of the tuberous sclerosis complex.

Authors:  Leah Marcotte; Peter B Crino
Journal:  Neuromolecular Med       Date:  2006       Impact factor: 3.843

5.  Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.

Authors:  Jing Zhou; Gayatri Shrikhande; Jing Xu; Renée M McKay; Dennis K Burns; Jane E Johnson; Luis F Parada
Journal:  Genes Dev       Date:  2011-08-01       Impact factor: 11.361

6.  Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1.

Authors:  Lindsay K Klofas; Brittany P Short; Chengwen Zhou; Robert P Carson
Journal:  Hum Mol Genet       Date:  2020-05-28       Impact factor: 6.150

7.  The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes.

Authors:  Jerzy Wegiel; Izabela Kuchna; Krzysztof Nowicki; Humi Imaki; Jarek Wegiel; Elaine Marchi; Shuang Yong Ma; Abha Chauhan; Ved Chauhan; Teresa Wierzba Bobrowicz; Mony de Leon; Leslie A Saint Louis; Ira L Cohen; Eric London; W Ted Brown; Thomas Wisniewski
Journal:  Acta Neuropathol       Date:  2010-03-03       Impact factor: 17.088

Review 8.  A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits.

Authors:  David M Feliciano; Tiffany V Lin; Nathaniel W Hartman; Christopher M Bartley; Cathryn Kubera; Lawrence Hsieh; Carlos Lafourcade; Rachel A O'Keefe; Angelique Bordey
Journal:  Int J Dev Neurosci       Date:  2013-02-26       Impact factor: 2.457

9.  Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.

Authors:  Robert P Carson; Cary Fu; Peggy Winzenburger; Kevin C Ess
Journal:  Hum Mol Genet       Date:  2012-10-09       Impact factor: 6.150

10.  Congenital subependymal giant cell astrocytoma: clinical considerations and expression of radial glial cell markers in giant cells.

Authors:  Ji Hoon Phi; Sung-Hye Park; Jong Hee Chae; Ki Ho Hong; Sung Sup Park; Ji Hyun Kang; Jong Kwan Jun; Byung-Kyu Cho; Kyu-Chang Wang; Seung-Ki Kim
Journal:  Childs Nerv Syst       Date:  2008-07-16       Impact factor: 1.475
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