| Literature DB >> 15851081 |
Ihsan Solaroglu1, Ozerk Okutan, Erkan Kaptanoglu, Etem Beskonakli, Kamer Kilinc.
Abstract
Oxidative stress may contribute to many of the pathophysiologic changes that occur after traumatic brain injury (TBI). There are a number of potential sources and mechanisms for oxygen free radical (OFR) production and lipid peroxidation after TBI. In this study, we investigate the time-dependent changes in xanthine oxidase (XO) activity and lipid peroxidation using a focal TBI animal model. We demonstrate that there is an immediate increase in lipid peroxidation by-products and in XO enzyme activity after TBI.Entities:
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Year: 2005 PMID: 15851081 DOI: 10.1016/j.jocn.2004.12.002
Source DB: PubMed Journal: J Clin Neurosci ISSN: 0967-5868 Impact factor: 1.961