Literature DB >> 15850827

The discovery of the CCR5 receptor antagonist, UK-427,857, a new agent for the treatment of HIV infection and AIDS.

Anthony Wood1, Duncan Armour.   

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Year:  2005        PMID: 15850827     DOI: 10.1016/S0079-6468(05)43007-6

Source DB:  PubMed          Journal:  Prog Med Chem        ISSN: 0079-6468


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  42 in total

Review 1.  The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery.

Authors:  Dennis A Smith; Li Di; Edward H Kerns
Journal:  Nat Rev Drug Discov       Date:  2010-12       Impact factor: 84.694

Review 2.  Chemokine receptor CCR5 antagonist maraviroc: medicinal chemistry and clinical applications.

Authors:  Guoyan G Xu; Jia Guo; Yuntao Wu
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295

3.  A population pharmacokinetic meta-analysis of maraviroc in healthy volunteers and asymptomatic HIV-infected subjects.

Authors:  Phylinda L S Chan; Barry Weatherley; Lynn McFadyen
Journal:  Br J Clin Pharmacol       Date:  2008-04       Impact factor: 4.335

4.  The effects of cotrimoxazole or tenofovir co-administration on the pharmacokinetics of maraviroc in healthy volunteers.

Authors:  Samantha Abel; Deborah Russell; Lyndsey A Whitlock; Caroline E Ridgway; Gary J Muirhead
Journal:  Br J Clin Pharmacol       Date:  2008-04       Impact factor: 4.335

Review 5.  Emerging paradigms in GPCR allostery: implications for drug discovery.

Authors:  Denise Wootten; Arthur Christopoulos; Patrick M Sexton
Journal:  Nat Rev Drug Discov       Date:  2013-08       Impact factor: 84.694

6.  The isolation of novel phage display-derived human recombinant antibodies against CCR5, the major co-receptor of HIV.

Authors:  Moria Shimoni; Alon Herschhorn; Yelena Britan-Rosich; Moshe Kotler; Itai Benhar; Amnon Hizi
Journal:  Viral Immunol       Date:  2013-08       Impact factor: 2.257

Review 7.  Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders.

Authors:  Liyun Wang; Bronwen Martin; Randall Brenneman; Louis M Luttrell; Stuart Maudsley
Journal:  J Pharmacol Exp Ther       Date:  2009-08-10       Impact factor: 4.030

8.  Maraviroc modelling strategy: use of early phase 1 data to support a semi-mechanistic population pharmacokinetic model.

Authors:  Barry Weatherley; Lynn McFadyen
Journal:  Br J Clin Pharmacol       Date:  2009-09       Impact factor: 4.335

Review 9.  Maraviroc.

Authors:  Natalie J Carter; Gillian M Keating
Journal:  Drugs       Date:  2007       Impact factor: 9.546

10.  Simian Immunodeficiency Virus SIVagm Efficiently Utilizes Non-CCR5 Entry Pathways in African Green Monkey Lymphocytes: Potential Role for GPR15 and CXCR6 as Viral Coreceptors.

Authors:  Nadeene E Riddick; Fan Wu; Kenta Matsuda; Sonya Whitted; Ilnour Ourmanov; Simoy Goldstein; Robert M Goeken; Ronald J Plishka; Alicia Buckler-White; Jason M Brenchley; Vanessa M Hirsch
Journal:  J Virol       Date:  2015-12-09       Impact factor: 5.103

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