Literature DB >> 15850634

Malaria.

Brian M Greenwood1, Kalifa Bojang, Christopher J M Whitty, Geoffrey A T Targett.   

Abstract

Malaria is the most important parasitic infection in people, accounting for more than 1 million deaths a year. Malaria has become a priority for the international health community and is now the focus of several new initiatives. Prevention and treatment of malaria could be greatly improved with existing methods if increased financial and labour resources were available. However, new approaches for prevention and treatment are needed. Several new drugs are under development, which are likely to be used in combinations to slow the spread of resistance, but the high cost of treatments would make sustainability difficult. Insecticide-treated bed-nets provide a simple but effective means of preventing malaria, especially with the development of longlasting nets in which insecticide is incorporated into the net fibres. One malaria vaccine, RTS,S/AS02, has shown promise in endemic areas and will shortly enter further trials. Other vaccines are being studied in clinical trials, but it will probably be at least 10 years before a malaria vaccine is ready for widespread use.

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Year:  2005        PMID: 15850634     DOI: 10.1016/S0140-6736(05)66420-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  193 in total

1.  Presence of IgE cells in human placenta is independent of malaria infection or chorioamnionitis.

Authors:  E Rindsjö; I Hulthén Varli; M F Ofori; M Lundquist; U Holmlund; N Papadogiannakis; A Scheynius
Journal:  Clin Exp Immunol       Date:  2006-05       Impact factor: 4.330

2.  Malaria burden in human population of Quetta, Pakistan.

Authors:  A M Tareen; M Rafique; A Wadood; M Qasim; H Rahman; S H Shah; K Khan; G S Pirkani
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2012-09-10

3.  A model of host response to a multi-stage pathogen.

Authors:  Edgar Delgado-Eckert; Michael Shapiro
Journal:  J Math Biol       Date:  2010-10-02       Impact factor: 2.259

4.  Taking away the sting of malaria.

Authors:  Sally Murray
Journal:  CMAJ       Date:  2006-01-17       Impact factor: 8.262

5.  Polymeric linear Peptide chimeric vaccine-induced antimalaria immunity is associated with enhanced in vitro antigen loading.

Authors:  Luciana M Silva-Flannery; Monica Cabrera-Mora; Megan Dickherber; Alberto Moreno
Journal:  Infect Immun       Date:  2009-02-23       Impact factor: 3.441

Review 6.  Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells.

Authors:  Kwang-Chul Kwon; Dheeraj Verma; Nameirakpam D Singh; Roland Herzog; Henry Daniell
Journal:  Adv Drug Deliv Rev       Date:  2012-10-23       Impact factor: 15.470

7.  Antimalarial chemotherapy: orally curative artemisinin-derived trioxane dimer esters.

Authors:  Ryan C Conyers; Jennifer R Mazzone; Abhai K Tripathi; David J Sullivan; Gary H Posner
Journal:  Bioorg Med Chem Lett       Date:  2014-11-27       Impact factor: 2.823

8.  Does Insecticide Treated Mosquito Nets (ITNs) prevent clinical malaria in children aged between 6 and 59 months under program setting?

Authors:  Yunis Mussema Abdella; Amare Deribew; Wodwoson Kassahun
Journal:  J Community Health       Date:  2009-04

9.  Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria.

Authors:  Tina Dasgupta; Penchit Chitnumsub; Sumalee Kamchonwongpaisan; Cherdsak Maneeruttanarungroj; Sara E Nichols; Theresa M Lyons; Julian Tirado-Rives; William L Jorgensen; Yongyuth Yuthavong; Karen S Anderson
Journal:  ACS Chem Biol       Date:  2009-01-16       Impact factor: 5.100

10.  Reversal agent and linker variants of reversed chloroquines: activities against Plasmodium falciparum.

Authors:  Simeon Andrews; Steven J Burgess; Deborah Skaalrud; Jane Xu Kelly; David H Peyton
Journal:  J Med Chem       Date:  2010-01-28       Impact factor: 7.446

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