| Literature DB >> 15848163 |
Salah E Abdel-Ghany1, Jason L Burkhead, Kathryn A Gogolin, Nuria Andrés-Colás, Jared R Bodecker, Sergi Puig, Lola Peñarrubia, Marinus Pilon.
Abstract
In plant chloroplasts two superoxide dismutase (SOD) activities occur, FeSOD and Cu/ZnSOD, with reciprocal regulation in response to copper availability. This system presents a unique model to study the regulation of metal-cofactor delivery to an organelle. The Arabidopsis thaliana gene AtCCS encodes a functional homolog to yeast Ccs1p/Lys7p, a copper chaperone for SOD. The AtCCS protein was localized to chloroplasts where it may supply copper to the stromal Cu/ZnSOD. AtCCS mRNA expression levels are upregulated in response to Cu-feeding and senescence. We propose that AtCCS expression is regulated to allow the most optimal use of Cu for photosynthesis.Entities:
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Year: 2005 PMID： 15848163 DOI： 10.1016/j.febslet.2005.03.025
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124