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Literature DB >> 15846372

The dsRNA-dependent protein kinase, PKR and cell death.

G N Barber.

Abstract

Entities: Gene

Mesh：

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Year: 2005 PMID： 15846372 DOI： 10.1038/sj.cdd.4401643

Source DB: PubMed Journal: Cell Death Differ ISSN： 1350-9047 Impact factor: 15.828

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41 in total

1. Molecular mechanism by which palmitate inhibits PKR autophosphorylation.

Authors: Hyunju Cho; Shayantani Mukherjee; Pratheeba Palasuberniam; Lisa Pillow; Betul Bilgin; Catherine Nezich; S Patrick Walton; Michael Feig; Christina Chan
Journal: Biochemistry Date: 2011-01-24 Impact factor: 3.162

2. Molecular basis for PKR activation by PACT or dsRNA.

Authors: Shoudong Li; Gregory A Peters; Keyang Ding; Xiaolun Zhang; Jun Qin; Ganes C Sen
Journal: Proc Natl Acad Sci U S A Date: 2006-06-19 Impact factor: 11.205

3. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis.

Authors: Kenneth W Adams; Geoffrey M Cooper
Journal: J Biol Chem Date: 2007-01-02 Impact factor: 5.157

Review 4. The response of mammalian cells to double-stranded RNA.

Authors: Michael P Gantier; Bryan R G Williams
Journal: Cytokine Growth Factor Rev Date: 2007-08-14 Impact factor: 7.638

5. Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii.

Authors: Jana Narasimhan; Bradley R Joyce; Arunasalam Naguleswaran; Aaron T Smith; Meredith R Livingston; Stacy E Dixon; Isabelle Coppens; Ronald C Wek; William J Sullivan
Journal: J Biol Chem Date: 2008-04-16 Impact factor: 5.157

The dsRNA-dependent protein kinase, PKR and cell death.

1. Molecular mechanism by which palmitate inhibits PKR autophosphorylation.

2. Molecular basis for PKR activation by PACT or dsRNA.

3. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis.

Review 4. The response of mammalian cells to double-stranded RNA.

5. Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii.

Review 6. Heat stress response of male germ cells.

7. 2-methoxyestradiol-induced cell death in osteosarcoma cells is preceded by cell cycle arrest.

8. Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.

9. The chemotherapeutic agent bortezomib induces the formation of stress granules.

10. Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2.