Literature DB >> 15845758

A pilot study of standardized treatment in geriatric bipolar disorder.

Ariel G Gildengers1, Benoit H Mulsant, Amy E Begley, Mary McShea, Jacqueline A Stack, Mark D Miller, Andrea Fagiolini, David J Kupfer, Robert C Young, Charles F Reynolds.   

Abstract

OBJECTIVE: The authors sought to determine the feasibility of treating elderly adults with bipolar disorder under standardized-treatment conditions.
METHODS: Thirty-one patients age 60 and older with bipolar disorder were treated in standardized pathways. Mood state was checked at each study visit with the Hamilton Rating Scale for Depression-17 item (Ham-D-17) and the Young Mania Rating Scale (YMRS).
RESULTS: Defining "well days" as both Ham-D and YMRS scores of <or=10, the mean percentage of well days was 72.5 (range: 0%-100%) over study participation.
CONCLUSIONS: Treating older adults with bipolar disorder under standardized treatment is feasible and is associated with low symptom levels. However, most older adults with bipolar disorder do not experience sustained recovery.

Entities:  

Mesh:

Year:  2005        PMID: 15845758     DOI: 10.1176/appi.ajgp.13.4.319

Source DB:  PubMed          Journal:  Am J Geriatr Psychiatry        ISSN: 1064-7481            Impact factor:   4.105


  17 in total

1.  Enhancing medication adherence: in older adults with bipolar disorder.

Authors:  Colin A Depp; Barry D Lebowitz
Journal:  Psychiatry (Edgmont)       Date:  2007-06

2.  Cognition in older adults with bipolar disorder versus major depressive disorder.

Authors:  Ariel G Gildengers; Meryl A Butters; Denise Chisholm; Stewart J Anderson; Amy Begley; Margo Holm; Joan C Rogers; Charles F Reynolds; Benoit H Mulsant
Journal:  Bipolar Disord       Date:  2012-03       Impact factor: 6.744

3.  Multisite, open-label, prospective trial of lamotrigine for geriatric bipolar depression: a preliminary report.

Authors:  Martha Sajatovic; Ariel Gildengers; Rayan K Al Jurdi; Laszlo Gyulai; Kristin A Cassidy; Rebecca L Greenberg; Martha L Bruce; Benoit H Mulsant; Thomas Ten Have; Robert C Young
Journal:  Bipolar Disord       Date:  2011-05       Impact factor: 6.744

4.  Longer lithium exposure is associated with better white matter integrity in older adults with bipolar disorder.

Authors:  Ariel G Gildengers; Meryl A Butters; Howard J Aizenstein; Megan M Marron; James Emanuel; Stewart J Anderson; Lisa A Weissfeld; James T Becker; Oscar L Lopez; Benoit H Mulsant; Charles F Reynolds
Journal:  Bipolar Disord       Date:  2014-09-25       Impact factor: 6.744

5.  Conceptual and methodological issues in designing a randomized, controlled treatment trial for geriatric bipolar disorder: GERI-BD.

Authors:  Robert C Young; Herbert C Schulberg; Ariel G Gildengers; Martha Sajatovic; Benoit H Mulsant; Laszlo Gyulai; John Beyer; Lauren Marangell; Mark Kunik; Thomas Ten Have; Martha L Bruce; Ruben Gur; Patricia Marino; Jovier D Evans; Charles F Reynolds; George S Alexopoulos
Journal:  Bipolar Disord       Date:  2010-02       Impact factor: 6.744

6.  Depression symptom ratings in geriatric patients with bipolar mania.

Authors:  Martha Sajatovic; Rayan Al Jurdi; Ariel Gildengers; Rebecca L Greenberg; Thomas Tenhave; Martha L Bruce; Benoit Mulsant; Robert C Young
Journal:  Int J Geriatr Psychiatry       Date:  2011-03-01       Impact factor: 3.485

7.  Two-year course of cognitive function and instrumental activities of daily living in older adults with bipolar disorder: evidence for neuroprogression?

Authors:  A G Gildengers; D Chisholm; M A Butters; S J Anderson; A Begley; M Holm; J C Rogers; C F Reynolds; B H Mulsant
Journal:  Psychol Med       Date:  2012-07-30       Impact factor: 7.723

8.  Antipsychotic treatments for the elderly: efficacy and safety of aripiprazole.

Authors:  Izchak Kohen; Paula E Lester; Sum Lam
Journal:  Neuropsychiatr Dis Treat       Date:  2010-03-24       Impact factor: 2.570

9.  The longitudinal course of cognition in older adults with bipolar disorder.

Authors:  Ariel G Gildengers; Benoit H Mulsant; Amy Begley; Sati Mazumdar; Adriana V Hyams; Charles F Reynolds Iii; David J Kupfer; Meryl A Butters
Journal:  Bipolar Disord       Date:  2009-08-28       Impact factor: 6.744

10.  Brain lithium levels and effects on cognition and mood in geriatric bipolar disorder: a lithium-7 magnetic resonance spectroscopy study.

Authors:  Brent P Forester; Chris C Streeter; Yosef A Berlow; Hua Tian; Megan Wardrop; Chelsea T Finn; David Harper; Perry F Renshaw; Constance M Moore
Journal:  Am J Geriatr Psychiatry       Date:  2009-01       Impact factor: 4.105

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