| Literature DB >> 15844943 |
Subeki Subeki1, Hideyuki Matsuura, Kosaku Takahashi, Masahiro Yamasaki, Osamu Yamato, Yoshimitsu Maede, Ken Katakura, Sumiko Kobayashi, Trimurningsih Trimurningsih, Chairul Chairul, Teruhiko Yoshihara.
Abstract
Bioassay-guided fractionation of boiled aqueous extracts from the whole plant of Phyllanthus niruri led to the isolation of 1-O-galloyl-6-O-luteoyl-alpha-d-glucose (1), with IC(50) values of 4.7 microg/mL against Babesia gibsoni and 1.4 microg/mL against Plasmodium falciparum in vitro. The known compounds beta-glucogallin (2), quercetin 3-O-beta-d-glucopyranosyl-(2-->1)-O-beta-d-xylopyranoside (3), beta-sitosterol, and gallic acid were also isolated. Structures of these compounds were elucidated on the basis of their chemical and spectroscopic data.Entities:
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Year: 2005 PMID： 15844943 DOI： 10.1021/np0497245
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050