Literature DB >> 15844888

Highly stereoselective additions of tin enolates to nitroalkenes and subsequent conversion of the nitro group into a nitrile.

Barbara Mendler1, Uli Kazmaier.   

Abstract

[reaction: see text] Sn-chelated glycine ester enolates are efficient nucleophiles for highly stereoselective 1,4-additions toward nitroolefins and subsequent reductions of the nitronate intermediates formed, giving rise to amino acid nitriles.

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Year:  2005        PMID： 15844888     DOI： 10.1021/ol050129j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method.

Authors:  Zong-Bo Xie; Na Wang; Ming-Yu Wu; Ting He; Zhang-Gao Le; Xiao-Qi Yu
Journal:  Beilstein J Org Chem       Date:  2012-04-11       Impact factor: 2.883

2.  Stereoselective Allylic Alkylations of Amino Ketones and Their Application in the Synthesis of Highly Functionalized Piperidines.

Authors:  Cynthia Prudel; Kai Huwig; Uli Kazmaier
Journal:  Chemistry       Date:  2020-02-21       Impact factor: 5.236
  2 in total

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