Accelerating MRI by skipped phase encoding and edge deghosting (SPEED).

A fast imaging method called skipped phase encoding and edge deghosting (SPEED) is introduced. The k-space is sparsely sampled into three interleaved datasets, each with a skip-size N and a relative shift in phase encoding (PE). These datasets are separately reconstructed by 2DFT and edge-enhanced by a differential filter in the PE direction, resulting in edge maps with phase-shifted aliasing ghosts. The sparseness of edges reduces the chance of ghost overlapping. Typical ghosted-edge maps can be adequately modeled with only two dominating ghost layers that are resolved from a set of three equations using least-square error minimization, yielding N ghost maps of different orders that can be registered and averaged into a single deghosted-edge map for noise and artifact reduction. Finally, the deghosted-edge map is transformed into a deghosted image by an inverse filter. A few central k-space lines are collected without PE skip to aid the inverse filtering. SPEED has been demonstrated by in vivo data to reduce scan time considerably without noticeable artifacts. It has various potential applications, such as MR angiography (MRA), where the signal itself is sparse. As an independent method, SPEED can be combined with other fast imaging methods for further acceleration. Copyright 2005 Wiley-Liss, Inc.