Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The immunoglobulin E receptor: expression and regulation.

Literature DB >> 15842956

The immunoglobulin E receptor: expression and regulation.

Abstract

The interaction of immunoglobulin E (IgE) and its receptors is critical for the manifestation of allergic disease. Currently, IgE receptors include the high-affinity Fc epsilonRI and the low-affinity Fc epsilonRII. Fc epsilonRI is a tetrameric or trimeric complex, and each has distinct expression patterns and unique functional consequences. In general, serum levels of IgE regulate Fc epsilonRI expression, and novel therapies that lower the concentration of IgE have provided insights into the contribution of this receptor in allergic disease. Newer therapies targeting Fc epsilonRI-signaling elements and the low-affinity IgE receptor, Fc epsilonRII (CD23), are being developed.

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 15842956 DOI： 10.1007/s11882-005-0037-5

Source DB: PubMed Journal: Curr Allergy Asthma Rep ISSN： 1529-7322 Impact factor: 4.919

42 in total

1. A second amplifier function for the allergy-associated Fc(epsilon)RI-beta subunit.

Authors: E Donnadieu; M H Jouvin; J P Kinet
Journal: Immunity Date: 2000-05 Impact factor: 31.745

2. The high-affinity IgE receptor (FcepsilonRI) blocks apoptosis in normal human monocytes.

Authors: N Katoh; S Kraft; J H Wessendorf; T Bieber
Journal: J Clin Invest Date: 2000-01 Impact factor: 14.808

3. Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival.

Authors: J Kalesnikoff; M Huber; V Lam; J E Damen; J Zhang; R P Siraganian; G Krystal
Journal: Immunity Date: 2001-06 Impact factor: 31.745

4. Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.

Authors: D W MacGlashan; B S Bochner; D C Adelman; P M Jardieu; A Togias; J McKenzie-White; S A Sterbinsky; R G Hamilton; L M Lichtenstein
Journal: J Immunol Date: 1997-02-01 Impact factor: 5.422

5. Evidence for a differential expression of the FcepsilonRIgamma chain in dendritic cells of atopic and nonatopic donors.

Authors: Natalija Novak; Carmen Tepel; Susanne Koch; Klaudia Brix; Thomas Bieber; Stefan Kraft
Journal: J Clin Invest Date: 2003-04 Impact factor: 14.808

6. Expression of high-affinity IgE receptors (Fc epsilon RI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: relationship to total serum IgE concentrations.

Authors: B S Sihra; O M Kon; J A Grant; A B Kay
Journal: J Allergy Clin Immunol Date: 1997-05 Impact factor: 10.793

Review 7. IgE receptors.

Authors: N Novak; S Kraft; T Bieber
Journal: Curr Opin Immunol Date: 2001-12 Impact factor: 7.486

8. Expression and modulation of FcepsilonRIalpha and FcepsilonRIbeta in human blood basophils.

Authors: S S Saini; J J Richardson; C Wofsy; S Lavens-Phillips; B S Bochner; D W Macglashan
Journal: J Allergy Clin Immunol Date: 2001-05 Impact factor: 10.793

9. Dendritic cells in normal and asthmatic airways: expression of the alpha subunit of the high affinity immunoglobulin E receptor (Fc epsilon RI -alpha).

Authors: J M Tunon-De-Lara; A E Redington; P Bradding; M K Church; J A Hartley; A E Semper; S T Holgate
Journal: Clin Exp Allergy Date: 1996-06 Impact factor: 5.018

Review 10. Omalizumab and the treatment of allergic rhinitis.

Authors: Michael A Kaliner
Journal: Curr Allergy Asthma Rep Date: 2004-05 Impact factor: 4.806

3 in total

1. House dust allergy and immunotherapy.

Authors: Wayne R Thomas
Journal: Hum Vaccin Immunother Date: 2012-08-16 Impact factor: 3.452

2. Age-Related Cataract Is Associated with Elevated Serum Immunoglobulin E Levels in the South Korean Population: A Cross-Sectional Study.

Authors: Tae Keun Yoo; Sun Woong Kim; Kyoung Yul Seo
Journal: PLoS One Date: 2016-11-18 Impact factor: 3.240

3. Neuronal FcεRIα directly mediates ocular itch via IgE-immune complex in a mouse model of allergic conjunctivitis.

Authors: Huan Cui; Fan Liu; Yehong Fang; Tao Wang; Bo Yuan; Chao Ma
Journal: J Neuroinflammation Date: 2022-02-23 Impact factor: 8.322

3 in total