Literature DB >> 15842351

Independent association of von Willebrand factor with surrogate markers of atherosclerosis in middle-aged asymptomatic subjects.

J A Páramo1, O Beloqui, I Colina, J Diez, J Orbe.   

Abstract

Von Willebrand factor (VWF) is considered a reliable marker of endothelial damage. Plasma levels of VWF were measured in 857 middle-aged subjects (80.4% men) free of clinically overt atherosclerotic disease, in relation to cardiovascular risk factors, carotid intima-media thickness (IMT) and microalbuminuria, two established surrogate markers of atherosclerosis. There was linear trend for the increase of VWF, carotid IMT (p < 0.001) and microalbuminuria (p = 0.018). The association between VEF and both markers remained statistically significant after adjusting for cardiovascular risk factors and inflammatory markers (p < 0.01). In conclusion, VWF was independently associated with both structural and functional surrogates of atherosclerosis in asymptomatic subjects, thus representing a systemic biomarker of subclinical atherosclerosis.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15842351     DOI： 10.1111/j.1538-7836.2005.01305.x

Source DB:  PubMed          Journal:  J Thromb Haemost        ISSN： 1538-7836            Impact factor:   5.824


  9 in total

1.  Prothrombotic markers in asymptomatic dyslipidemic subjects.

Authors:  David Karasek; Helena Vaverkova; Milan Halenka; Dagmar Jackuliakova; Zdenek Frysak; Ludek Slavik; Dalibor Novotny
Journal:  J Thromb Thrombolysis       Date:  2011-01       Impact factor: 2.300

2.  Early detection of C-reactive protein and von Willebrand factor levels in Malaysian patients with acute coronary syndrome.

Authors:  Wen Ni Tiong; Edmund Ui Hang Sim; Alan Yean Yip Fong; Tiong Kiam Ong
Journal:  J Cardiovasc Dis Res       Date:  2013-02-27

3.  Aging and ABO blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms.

Authors:  S Albánez; K Ogiwara; A Michels; W Hopman; J Grabell; P James; D Lillicrap
Journal:  J Thromb Haemost       Date:  2016-04-27       Impact factor: 5.824

4.  Associations of D-dimer and von Willebrand factor with atherosclerosis in Japanese and white men.

Authors:  Ryoko W Azuma; Takashi Kadowaki; Aiman El-Saed; Hirotsugu Ueshima; Kim Sutton-Tyrrell; Yasuyuki Nakamura; Daniel Edmundowicz; Yoshiki Ueno; Rhobert W Evans; Aya Kadota; Lewis H Kuller; Kiyoshi Murata; Tomoko Takamiya; Sayaka Kadowaki; J David Curb; Akira Sekikawa
Journal:  Acta Cardiol       Date:  2010-08       Impact factor: 1.718

5.  Elevated fibrinogen levels and subsequent subclinical atherosclerosis: the CARDIA Study.

Authors:  David Green; Nancy Foiles; Cheeling Chan; Pamela J Schreiner; Kiang Liu
Journal:  Atherosclerosis       Date:  2008-07-03       Impact factor: 5.162

6.  [The function and clinical value of Von Willebrand factor propeptide].

Authors:  Jie Yin; Changgeng Ruan
Journal:  Zhonghua Xue Ye Xue Za Zhi       Date:  2015-10

7.  The monomeric C-reactive protein level is associated with the increase in carotid plaque number in patients with subclinical carotid atherosclerosis.

Authors:  Ivan Melnikov; Sergey Kozlov; Olga Pogorelova; Maria Tripoten; Leyla Khamchieva; Olga Saburova; Yuliya Avtaeva; Maria Zvereva; Evgeny Matroze; Tatiana Kuznetsova; Lyudmila Prokofieva; Tatiana Balakhonova; Zufar Gabbasov
Journal:  Front Cardiovasc Med       Date:  2022-07-22

8.  Integrating soluble biomarkers and imaging technologies in the identification of vulnerable atherosclerotic patients.

Authors:  José A Páramo; José A Rodríguez Ja; Josune Orbe
Journal:  Biomark Insights       Date:  2007-02-07

9.  Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis and Low Cardiovascular Risk: The Role of von Willebrand Factor Activity.

Authors:  Gorica G Ristić; Vesna Subota; Toplica Lepić; Dejana Stanisavljević; Branislava Glišić; Arsen D Ristić; Milan Petronijević; Dušan Z Stefanović
Journal:  PLoS One       Date:  2015-08-06       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.