OBJECTIVE: The aim of this study was to report our experience with malignant and borderline soft tissue tumours (STS) of the head and neck region in the period 1977-2000. DESIGN: Retrospective case study including new evaluation of histological specimens. SETTING: Tertiary centre, single centre. PARTICIPANTS: Review of patient's records and new evaluation of pathological specimens were made for 66 patients. After evaluation only 36 patients (26 men and 10 women) still met present criteria for a STS in head and neck in adults. RESULTS: The original histological diagnosis was changed in 27 (41%) of the 66 patients with a primary diagnosis of sarcoma. After review the most common histological diagnoses were leiomyosarcoma (5) and rhabdomyosarcoma (5). Overall 5-year survival rate was 60%. Overall 5-year disease-free survival rate was 44%. The study showed that both tumour grade and surgical margin had a statistically significant impact on survival. No relation was found between survival and tumour size or age. CONCLUSION: The grave prognosis especially for high-grade tumours emphasizes the need for improved treatment strategies. Furthermore, conclusions from older studies concerning prognosis may be obsolete as approximately 40% of tumours previously diagnosed as sarcomas may be invalid by present day standards.
OBJECTIVE: The aim of this study was to report our experience with malignant and borderline soft tissue tumours (STS) of the head and neck region in the period 1977-2000. DESIGN: Retrospective case study including new evaluation of histological specimens. SETTING: Tertiary centre, single centre. PARTICIPANTS: Review of patient's records and new evaluation of pathological specimens were made for 66 patients. After evaluation only 36 patients (26 men and 10 women) still met present criteria for a STS in head and neck in adults. RESULTS: The original histological diagnosis was changed in 27 (41%) of the 66 patients with a primary diagnosis of sarcoma. After review the most common histological diagnoses were leiomyosarcoma (5) and rhabdomyosarcoma (5). Overall 5-year survival rate was 60%. Overall 5-year disease-free survival rate was 44%. The study showed that both tumour grade and surgical margin had a statistically significant impact on survival. No relation was found between survival and tumour size or age. CONCLUSION: The grave prognosis especially for high-grade tumours emphasizes the need for improved treatment strategies. Furthermore, conclusions from older studies concerning prognosis may be obsolete as approximately 40% of tumours previously diagnosed as sarcomas may be invalid by present day standards.
Authors: Hari Ram; Satish Kumar; S N Singh; Pramod Kumar; Geeta Singh; Roop Ganguly; Mala Sagar; Debraj Howlader Journal: Ann Maxillofac Surg Date: 2022-02-01
Authors: Isabela Alves Pacheco; Ana Paula Negreiros Nunes Alves; Mário Rogério Lima Mota; Paulo César de Almeida; Marcelo Esmeraldo Holanda; Eric Fernandes de Souza; Fabricio Bitu Sousa Journal: Braz J Otorhinolaryngol Date: 2011-06