BACKGROUND: The long-term functional outcome after thoracoabdominal resection has to be better evaluated. A study was performed to evaluate patients after a similar operation both in terms of physical function and health-related quality of life (HRQL). METHODS: Eighteen patients were evaluated 2 years after a thoracoabdominal resection. Respiratory function, physical performance and range of motion in shoulder, thorax and spine were recorded. HQRL was assessed by EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30) and EORTC QLQ-OES18 (Oeophageal module). RESULTS: Two years after surgery, respiratory function (forced vital capacity and forced expiratory volume in 1 s) was significantly impaired compared to preoperative values (p < 0.05). The physical performance was significantly reduced as measured by a functional stand-up test (p < 0.05) and the handgrip force (p < 0.001). Shoulder range of motion, thoracic lateral flexion and C7 to wall were within normal ranges, thoracic flexion significantly greater (p < 0.01) but chest expansion significantly decreased (p < 0.01) compared to controls. HQRL was comparable to age- and sex-matched population norms for most of the functions. A clinical significant difference was, however, found for diarrhoea, dyspnoea, appetite loss and fatigue. CONCLUSION: Within a 2-year period, each individual regains most of the respiratory and physical performances and HRQL after a thoracoabdominal resection.
BACKGROUND: The long-term functional outcome after thoracoabdominal resection has to be better evaluated. A study was performed to evaluate patients after a similar operation both in terms of physical function and health-related quality of life (HRQL). METHODS: Eighteen patients were evaluated 2 years after a thoracoabdominal resection. Respiratory function, physical performance and range of motion in shoulder, thorax and spine were recorded. HQRL was assessed by EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30) and EORTC QLQ-OES18 (Oeophageal module). RESULTS: Two years after surgery, respiratory function (forced vital capacity and forced expiratory volume in 1 s) was significantly impaired compared to preoperative values (p < 0.05). The physical performance was significantly reduced as measured by a functional stand-up test (p < 0.05) and the handgrip force (p < 0.001). Shoulder range of motion, thoracic lateral flexion and C7 to wall were within normal ranges, thoracic flexion significantly greater (p < 0.01) but chest expansion significantly decreased (p < 0.01) compared to controls. HQRL was comparable to age- and sex-matched population norms for most of the functions. A clinical significant difference was, however, found for diarrhoea, dyspnoea, appetite loss and fatigue. CONCLUSION: Within a 2-year period, each individual regains most of the respiratory and physical performances and HRQL after a thoracoabdominal resection.
Authors: Marc Jacobs; Rhiannon C Macefield; Jane M Blazeby; Ida J Korfage; Mark I van Berge Henegouwen; Hanneke C J M de Haes; Ellen M Smets; Mirjam A G Sprangers Journal: Qual Life Res Date: 2012-10-20 Impact factor: 4.147
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Authors: E M L Verschuur; E W Steyerberg; H W Tilanus; S Polinder; M-L Essink-Bot; K T C Tran; A van der Gaast; L P S Stassen; E J Kuipers; P D Siersema Journal: Br J Cancer Date: 2008-12-09 Impact factor: 7.640
Authors: Rhiannon C Macefield; Marc Jacobs; Ida J Korfage; Joanna Nicklin; Robert N Whistance; Sara T Brookes; Mirjam A G Sprangers; Jane M Blazeby Journal: Trials Date: 2014-02-05 Impact factor: 2.279
Authors: Karina Tukanova; Enrica Papi; Sara Jamel; George B Hanna; Alison H McGregor; Sheraz R Markar Journal: J Thorac Dis Date: 2020-03 Impact factor: 3.005