Literature DB >> 1583669

The double disector: unbiased stereological estimation of the number of particles inside other particles.

N Marcussen1.   

Abstract

A double-disector method for obtaining estimates of the number of particles inside other particles, illustrated by an estimation of the average cell number in a glomerulus, has been developed. The method is suitable for paraffin-embedded tissue because it does not require knowledge about the section thickness. Most importantly, the estimate is absolutely unaffected by tissue shrinkage. The average number of cells in a human glomerulus is 2850 whereas in rats it is 580.

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Year:  1992        PMID: 1583669     DOI: 10.1111/j.1365-2818.1992.tb01496.x

Source DB:  PubMed          Journal:  J Microsc        ISSN: 0022-2720            Impact factor:   1.758


  3 in total

Review 1.  Efficient quantitative morphological phenotyping of genetically altered organisms using stereology.

Authors:  John Milton Lucocq
Journal:  Transgenic Res       Date:  2006-11-14       Impact factor: 2.788

Review 2.  If you assume, you can make an ass out of u and me': a decade of the disector for stereological counting of particles in 3D space.

Authors:  T M Mayhew; H J Gundersen
Journal:  J Anat       Date:  1996-02       Impact factor: 2.610

3.  Total numbers of glomeruli and individual glomerular cell types in the normal rat kidney.

Authors:  J F Bertram; M C Soosaipillai; S D Ricardo; G B Ryan
Journal:  Cell Tissue Res       Date:  1992-10       Impact factor: 5.249

  3 in total

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