| Literature DB >> 15835726 |
Kyoko Adachi1, Kaneo Kanoh, Puntip Wisespongp, Miyuki Nishijima, Yoshikazu Shizuri.
Abstract
The two new anti-dinoflagellates, clonostachysins A and B, were obtained from a marine sponge derived fungus Clonostachys rogersoniana strain HJK9. Their chemical structures were determined by spectroscopic studies as highly N-methylated cyclic peptides of the nine amino acids. The absolute stereochemistry was elucidated by the advanced Marfey's method. Both clonostachysins A and B exhibited a selectively inhibitory effect on a dinoflagellate Prorocentrum micans at 30 microM, but had no effect on other microalgae and bacteria even at 100 microM.Entities:
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Year: 2005 PMID： 15835726 DOI： 10.1038/ja.2005.17
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649