Literature DB >> 15832620

Depressed left ventricular contractile reserve diagnosed by dobutamine stress echocardiography in a patient with Duchenne muscular dystrophy.

Brenda L Y Wong1, Vincent A Mukkada, Larry W Markham, Linda H Cripe.   

Abstract

Cardiomyopathy is a leading cause of death in patients with Duchenne muscular dystrophy. Congestive heart failure is often sub-clinical and unrecognized as a result of the severe physical limitations of this patient population. We report the case of a 16-year-old boy with Duchenne muscular dystrophy who demonstrated normal left ventricular systolic function at rest by screening transthoracic echocardiogram. This patient, however, was noted to have depressed left ventricular contractile reserve by dobutamine stress echocardiography. Dobutamine stress echocardiography can have an important role in unmasking subclinical heart failure in this patient population.

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Year:  2005        PMID: 15832620     DOI: 10.1177/08830738050200031401

Source DB:  PubMed          Journal:  J Child Neurol        ISSN: 0883-0738            Impact factor:   1.987


  3 in total

1.  Effects of steroids and angiotensin converting enzyme inhibition on circumferential strain in boys with Duchenne muscular dystrophy: a cross-sectional and longitudinal study utilizing cardiovascular magnetic resonance.

Authors:  Kan N Hor; Wojciech Mazur; Michael D Taylor; Hussein R Al-Khalidi; Linda H Cripe; John L Jefferies; Subha V Raman; Eugene S Chung; Kathi J Kinnett; Katelyn Williams; William M Gottliebson; D Woodrow Benson
Journal:  J Cardiovasc Magn Reson       Date:  2011-10-19       Impact factor: 5.364

2.  Reduced Myocardial Reserve in Young X-Linked Muscular Dystrophy Mice Diagnosed by Two-Dimensional Strain Analysis Combined with Stress Echocardiography.

Authors:  Zhenzhou Li; Ying Li; Li Zhang; Xiaoying Zhang; Rebecca Sullivan; Xiaojie Ai; Christopher Szeto; Angela Cai; Longjian Liu; Weidong Xiao; Quanshui Li; Shuping Ge; Xiongwen Chen
Journal:  J Am Soc Echocardiogr       Date:  2017-05-13       Impact factor: 5.251

3.  Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance.

Authors:  Gunnar M Buyse; Gerry Van der Mieren; Michael Erb; Jan D'hooge; Paul Herijgers; Erik Verbeken; Alejandro Jara; An Van Den Bergh; Luc Mertens; Isabelle Courdier-Fruh; Patrizia Barzaghi; Thomas Meier
Journal:  Eur Heart J       Date:  2008-09-10       Impact factor: 29.983

  3 in total

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