BACKGROUND: There are limited data pertaining to the factors influencing the incidence and persistence of sleep symptoms in the elderly. The purpose of this study was to determine the incidence and nonremission rates of the following sleep symptoms: trouble falling asleep (TFA), frequent awakenings (FA), and excessive daytime sleepiness (EDS) in the Cardiovascular Health Study (CHS), a prospective multicenter study of cardiovascular disease in a large cohort of elderly adults. Factors influencing these rates were assessed as well. METHODS: 4467 participants in CHS were surveyed for the presence of TFA, FA, and EDS as well as other health problems at their baseline examination and at a follow-up examination 1 to 4 years later. RESULTS: Annualized incidence and nonremission rates were the following: TFA (2.8% and 15.4%), FA (12.3% and 22.7%), and EDS (4.4% and 13.4%). Women were more likely to have incident and persistent TFA. Depression was the primary factor predicting the incidence of all three sleep symptoms. However, other health conditions, including respiratory symptoms and cardiovascular disease, and limitation in activities of daily living were important as well. Depression also was the most important factor associated with persistence of these sleep symptoms. The role of other health conditions in determining nonremission was much more limited. CONCLUSIONS: Incidence of sleep disturbances in the elderly is related to depression, health conditions, and physical functioning. However, persistence of sleep disturbances is best predicted by the presence of depression.
BACKGROUND: There are limited data pertaining to the factors influencing the incidence and persistence of sleep symptoms in the elderly. The purpose of this study was to determine the incidence and nonremission rates of the following sleep symptoms: trouble falling asleep (TFA), frequent awakenings (FA), and excessive daytime sleepiness (EDS) in the Cardiovascular Health Study (CHS), a prospective multicenter study of cardiovascular disease in a large cohort of elderly adults. Factors influencing these rates were assessed as well. METHODS: 4467 participants in CHS were surveyed for the presence of TFA, FA, and EDS as well as other health problems at their baseline examination and at a follow-up examination 1 to 4 years later. RESULTS: Annualized incidence and nonremission rates were the following: TFA (2.8% and 15.4%), FA (12.3% and 22.7%), and EDS (4.4% and 13.4%). Women were more likely to have incident and persistent TFA. Depression was the primary factor predicting the incidence of all three sleep symptoms. However, other health conditions, including respiratory symptoms and cardiovascular disease, and limitation in activities of daily living were important as well. Depression also was the most important factor associated with persistence of these sleep symptoms. The role of other health conditions in determining nonremission was much more limited. CONCLUSIONS: Incidence of sleep disturbances in the elderly is related to depression, health conditions, and physical functioning. However, persistence of sleep disturbances is best predicted by the presence of depression.
Authors: Ravi Singareddy; Alexandros N Vgontzas; Julio Fernandez-Mendoza; Duanping Liao; Susan Calhoun; Michele L Shaffer; Edward O Bixler Journal: Sleep Med Date: 2012-03-17 Impact factor: 3.492
Authors: Julio Fernandez-Mendoza; Alexandros N Vgontzas; Ilia Kritikou; Susan L Calhoun; Duanping Liao; Edward O Bixler Journal: Sleep Date: 2015-03-01 Impact factor: 5.849
Authors: Alexandros N Vgontzas; Julio Fernandez-Mendoza; Edward O Bixler; Ravi Singareddy; Michele L Shaffer; Susan L Calhoun; Duanping Liao; Maria Basta; George P Chrousos Journal: Sleep Date: 2012-01-01 Impact factor: 5.849
Authors: Kathy C Richards; Paula K Roberson; Katherine Simpson; Corinne W Lambert; Donald L Bliwise; Catherine S Cole; Carol Enderlin; Valorie M Shue; Nadia Siddiqui; James Silas Williams Journal: Sleep Date: 2008-02 Impact factor: 5.849