Literature DB >> 15830490

In vitro uptake of isometamidium and diminazene by Trypanosoma brucei.

P Girgis-Takla, D M James.   

Abstract

The cattle trypanocide, isometamidium, was readily taken up by inactivated Trypanosoma brucei, while its uptake by living parasites was reduced or inhibited by plasma. In both respects isometamidium differs from diminazene.

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Year:  1974        PMID： 15830490      PMCID： PMC444654          DOI： 10.1128/AAC.6.3.372

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  STUDIES ON ISOMETAMIDIUM. DEPOTS OF ISOMETAMIDIUM IN MICE AND RATS AND THEIR IMPORTANCE FOR PROPHYLAXIS AGAINST TRYPANOSOMA CONGOLENSE.

Authors:  J HILL; J A MCFADZEAN
Journal:  Trans R Soc Trop Med Hyg       Date:  1963-11       Impact factor: 2.184

2.  The oxygen uptake of Trypanosoma lewisi and Trypanosoma equiperdum, with especial reference to oxygen consumption in the presence of amino-acids.

Authors:  J P THURSTON
Journal:  Parasitology       Date:  1958-05       Impact factor: 3.234

3.  The chemotherapeutic action of phenanthridine compounds. IV. Activity in vitro.

Authors:  J A LOCK
Journal:  Br J Pharmacol Chemother       Date:  1950-09

4.  Physiologic disposition and intracellular localization of isometamidium.

Authors:  F S Philips; S S Sternberg; A P Cronin; J E Sodergren; P M Vidal
Journal:  Cancer Res       Date:  1967-02       Impact factor: 12.701

5.  Separation of trypanosomes from the blood of infected rats and mice by anion-exchangers.

Authors:  S M Lanham
Journal:  Nature       Date:  1968-06-29       Impact factor: 49.962

6.  The trypanocidal action of homidium, quinapyramine and suramin.

Authors:  F HAWKING; A B SEN
Journal:  Br J Pharmacol Chemother       Date:  1960-12
  6 in total
  1 in total

1.  Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake.

Authors:  Jane C Munday; Karla E Rojas López; Anthonius A Eze; Vincent Delespaux; Jan Van Den Abbeele; Tim Rowan; Michael P Barrett; Liam J Morrison; Harry P de Koning
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2013-02-10       Impact factor: 4.077
  1 in total

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